3-(1,3-Benzodioxol-5-yl)serine

Base Information

Chemical Name:3-(1,3-Benzodioxol-5-yl)serine
CAS No.:56672-56-1
Molecular Formula:C₁₀H₁₁NO₅
Molecular Weight:225.201
Hs Code.:
NSC Number:158552
UNII:9P6AQ75H63
Nikkaji Number:J138.285C
Mol file:56672-56-1.mol

Synonyms:56672-56-1;3-(1,3-benzodioxol-5-yl)serine;3,4-methylenedioxyphenylserine;9P6AQ75H63;UNII-9P6AQ75H63;2-Amino-3-(1,3-benzodioxol-5-yl)-3-hydroxypropionic acid;2-amino-3-(1,3-benzodioxol-5-yl)-3-hydroxypropanoic acid;alpha-Amino-beta-hydroxy-1,3-benzodioxole-5-propanoic acid;1,3-Benzodioxole-5-propanoic acid, alpha-amino-beta-hydroxy-;NSC158552;SCHEMBL5279500;AMY19626;AKOS015156274;NSC-158552;EN300-2005015;AJ-190/13485007;2-amino-3-(1,3-dioxaindan-5-yl)-3-hydroxypropanoic acid;.ALPHA.-AMINO-.BETA.-HYDROXY-1,3-BENZODIOXOLE-5-PROPANOIC ACID;1,3-BENZODIOXOLE-5-PROPANOIC ACID, .ALPHA.-AMINO-.BETA.-HYDROXY-

Suppliers and Price of 3-(1,3-Benzodioxol-5-yl)serine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-AMINO-3-(1,3-BENZODIOXOL-5-YL)-3-HYDROXYPROPIONIC ACID 95.00%
5MG
$ 505.42

Total 9 raw suppliers

Chemical Property of 3-(1,3-Benzodioxol-5-yl)serine

Chemical Property:

XLogP3:-2.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:225.06372245
Heavy Atom Count:16
Complexity:272

Purity/Quality:

99%, ^*data from raw suppliers

2-AMINO-3-(1,3-BENZODIOXOL-5-YL)-3-HYDROXYPROPIONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1OC2=C(O1)C=C(C=C2)C(C(C(=O)O)N)O

Technology Process of 3-(1,3-Benzodioxol-5-yl)serine

There total 2 articles about 3-(1,3-Benzodioxol-5-yl)serine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.1%

: 56672-56-1
2-amino-3-hydroxy-3-(3,4-methylenedioxyphenyl)propanoic acid

Guidance literature:

Reference yield: 70.0%

: 120-57-0,30024-74-9
piperonal

: 56-40-6,18875-39-3,25718-94-9
glycine

: 56672-56-1
2-amino-3-hydroxy-3-(3,4-methylenedioxyphenyl)propanoic acid

Guidance literature:: With potassium hydroxide; In methanol; toluene; at 15 - 20 ℃; for 18h;

Reference yield:

: 56672-56-1
2-amino-3-hydroxy-3-(3,4-methylenedioxyphenyl)propanoic acid

: 123474-73-7,141858-84-6
4-keto-2-azapodophyllotoxin

Guidance literature:: Multi-step reaction with 7 steps

1: K₂CO₃ / H₂O

2: K₂CO₃ / acetone

3: 98 percent / Dess-Martin reagent / CH₂Cl₂

4: 81 percent / BF₃*OEt₂ / CH₂Cl₂

5: LiBH₄ / tetrahydrofuran / Heating

6: NaOMe

7: 68 percent / CF₃SO₃H / various solvent(s) / Ambient temperature

With lithium borohydride; trifluorormethanesulfonic acid; boron trifluoride diethyl etherate; sodium methylate; potassium carbonate; Dess-Martin periodane; In tetrahydrofuran; dichloromethane; water; acetone;
DOI:10.3987/COM-91-S94