2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl-sulfonyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid

Base Information

Chemical Name:2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl-sulfonyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid
CAS No.:1373829-76-5
Molecular Formula:C₃₂H₃₄N₂O₁₁S
Molecular Weight:654.695
Hs Code.:

2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl-sulfonyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid

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Chemical Property of 2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl-sulfonyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid

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Technology Process of 2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl-sulfonyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid

There total 2 articles about 2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl-sulfonyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.6%

: 1373829-76-5
2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl-sulfonyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 20.3333h;

With trifluoroacetic acid; In dichloromethane; for 1h;

Reference yield:

: 27685-90-1
2-oxo-2,3-dihydrobenzo[d]oxazole-6-sulfonyl chloride

: C₂₅H₃₀NO₇Pol

: 1373829-76-5
2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl-sulfonyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid

Guidance literature:: 2-oxo-2,3-dihydrobenzo[d]oxazole-6-sulfonyl chloride; C₂₅H₃₀NO₇Pol; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 20h; Combinatorial reaction / High throughput screening (HTS); solid phase reaction;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h; Combinatorial reaction / High throughput screening (HTS); solid phase reaction;
DOI:10.1021/jm201747c