ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

Base Information

Chemical Name:ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS No.:30720-25-3
Molecular Formula:C11H12ClN3O2
Molecular Weight:253.688
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10440817
Mol file:30720-25-3.mol

Synonyms:30720-25-3;ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate;Ethyl-4-chloro-1-ethyl-1H-pyrazole [3,4]pyridine-5-carboxylate;ethyl 4-chloro-1-ethylpyrazolo[3,4-b]pyridine-5-carboxylate;4-CHLORO-1-ETHYL-1H-PYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID ETHYL ESTER;1h-pyrazolo[3,4-b]pyridine-5-carboxylic acid,4-chloro-1-ethyl-,ethyl ester;SCHEMBL582528;DTXSID10440817;RCQMGWFLFNPCJC-UHFFFAOYSA-N;AMY35250;MFCD06656752;AKOS015961694;PB14444;4-Chloro-6-methyl-m-phenylenediisocyanate;AC-14638;AS-37783;CS-0049469;EN300-7418881;A876106;ethyl 4-chloro-1-ethylpyrazolo[4,5-e]pyridine-5-carboxylate;ethyl 4-chloro-1-ethyl-1H-pyrazolo [3,4-b]pyridine-5-carboxylate;Ethyl 4-chloro-1-ethyl-1H-pyrazolo-[3,4-b]pyridine-5-carboxylate;ethyl-4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate;ethyl4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate;4-Chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid, ethyl ester

Suppliers and Price of ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl4-chloro-1-ethyl-1H-pyrazolo-[3,4-b]pyridine-5-carboxylate 95+%
1g
$ 644.00

Labseeker
ethyl-4-chloro-1-ethyl-1h-pyrazole[3,4]pyridine-5-carboxylate 95
10g
$ 2383.00

Crysdot
Ethyl4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate 95+%
10g
$ 2375.00

Crysdot
Ethyl4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate 95+%
1g
$ 452.00

Crysdot
Ethyl4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate 95+%
5g
$ 1395.00

Chemenu
ethyl4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate 95+%
1g
$ 255.00

Chemenu
ethyl4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate 95+%
10g
$ 1280.00

Chemenu
ethyl4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate 95+%
5g
$ 896.00

American Custom Chemicals Corporation
ETHYL-4-CHLORO-1-ETHYL-1H-PYRAZOLE (3,4)PYRIDINE-5-CARBOXYLATE 95.00%
5MG
$ 504.70

Alichem
Ethyl4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
10g
$ 2346.12

Total 17 raw suppliers

Chemical Property of ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:348.51°C at 760 mmHg
PKA:1.43±0.30(Predicted)
Flash Point:164.573°C
PSA：57.01000
Density:1.377g/cm³
LogP:2.28130
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:253.0618043
Heavy Atom Count:17
Complexity:290

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl4-chloro-1-ethyl-1H-pyrazolo-[3,4-b]pyridine-5-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C2=NC=C(C(=C2C=N1)Cl)C(=O)OCC

Technology Process of ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

There total 7 articles about ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 26823-99-4
[[(1-ethyl-5-pyrazolyl)amino]methylene]malonic acid diethyl ester

: 30720-25-3
ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

Guidance literature:: With trichlorophosphate; at 110 - 120 ℃; for 4h;

Reference yield:

: 30720-04-8
1-ethyl-4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester

: 30720-25-3
ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

Guidance literature:: With trichlorophosphate; Heating;
DOI:10.1021/jm00132a011

Reference yield:

: 3528-58-3
5-Amino-1-ethylpyrazole

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 30720-25-3
ethyl 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

Guidance literature:: 5-Amino-1-ethylpyrazole; diethyl 2-ethoxymethylenemalonate; at 160 ℃; for 7.5h;

With trichlorophosphate; In ethanol; for 13h; Heating / reflux;