CF3CO-2,Leu⁵>enkephalin

Base Information

Chemical Name:CF3CO-2,Leu⁵>enkephalin
CAS No.:99795-31-0
Molecular Formula:C₃₁H₃₈F₃N₅O₈
Molecular Weight:665.667
Hs Code.:

CF3CO-<D-Ala<sup>2</sup>,Leu<sup>5</sup>>enkephalin

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of CF3CO-2,Leu⁵>enkephalin

Chemical Property:

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Technology Process of CF3CO-2,Leu⁵>enkephalin

There total 5 articles about CF3CO-2,Leu⁵>enkephalin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73994-87-3
(S)-benzyl 2-((S)-2-amino-3-phenylpropanamido)-4-methylpentanoate hydrochloride

: 99795-31-0
CF3CO-2,Leu⁵>enkephalin

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent

2: anisole / CH₂Cl₂ / 1 h / 0 °C

3: 92 percent / triethylamine, 4-dimethylaminopyridine / dimethylformamide / 1 h / Ambient temperature

4: H₂ / Pd-C

With dmap; hydrogen; methoxybenzene; triethylamine; palladium on activated charcoal; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.33.4633

Reference yield:

: 67706-16-5
tert-butyloxycarbonyl-O-benzyl-L-tyrosyl-D-alanyl-glycine

: 99795-31-0
CF3CO-2,Leu⁵>enkephalin

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent

2: anisole / CH₂Cl₂ / 1 h / 0 °C

3: 92 percent / triethylamine, 4-dimethylaminopyridine / dimethylformamide / 1 h / Ambient temperature

4: H₂ / Pd-C

With dmap; hydrogen; methoxybenzene; triethylamine; palladium on activated charcoal; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.33.4633

Reference yield:

: 94790-22-4
Boc-(OBzl)-Tyr-D-Ala-Gly-Phe-Leu-OBzl

: 99795-31-0
CF3CO-2,Leu⁵>enkephalin

Guidance literature:: Multi-step reaction with 3 steps

1: anisole / CH₂Cl₂ / 1 h / 0 °C

2: 92 percent / triethylamine, 4-dimethylaminopyridine / dimethylformamide / 1 h / Ambient temperature

3: H₂ / Pd-C

With dmap; hydrogen; methoxybenzene; triethylamine; palladium on activated charcoal; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.33.4633