D-ribofuranosyl-oxazolidinone

Base Information

• Chemical Name: D-ribofuranosyl-oxazolidinone
• CAS No.: 2508-81-8
• Molecular Formula: C₆H₉NO₅
• Molecular Weight: 175.141
• European Community (EC) Number: 853-404-1
• Nikkaji Number: J469.754E

Synonyms:2508-81-8;D-ribofuranosyl-oxazolidinone;(3as,5r,6r,6ar)-6-hydroxy-5-(hydroxymethyl)-hexahydrofuro[2,3-d][1,3]oxazol-2-one;(3aS,5R,6R,6aR)-6-Hydroxy-5-(hydroxymethyl)tetrahydrofuro[2,3-d]oxazol-2(5H)-one;(3aS,5R,6R,6aR)-6-hydroxy-5-(hydroxymethyl)-3a,5,6,6a-tetrahydro-3H-furo[2,3-d][1,3]oxazol-2-one;AC8371;(3aS,5R,6R,6aR)-Tetrahydro-6-hydroxy-5-(hydroxymethyl)furo[2,3-d]oxazol-2(3H)-one;EN300-20098441

Chemical Property of D-ribofuranosyl-oxazolidinone

Chemical Property:

• XLogP3: -1.1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 175.04807239
• Heavy Atom Count: 12
• Complexity: 208

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(C1C(C2C(O1)NC(=O)O2)O)O
• Isomeric SMILES: C([C@@H]1[C@H]([C@@H]2[C@H](O1)NC(=O)O2)O)O

Technology Process of D-ribofuranosyl-oxazolidinone

There total 2 articles about D-ribofuranosyl-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1R,2R)-1-(2-amino-1,3-oxazol-5-yl)propane-1,2,3-triol (1165930-35-7) → 4,5-dihydro-1,2-dideoxy-α-D-ribofuranoso[1,2-d]-1,3-oxazol-2-one (2508-81-8) + 2-amino-β-D-arabinofurano[1',2':4,5]-oxazoline (27963-98-0) + 2-amino-(1,2-dideoxy-α-D-ribofurano)<1,2-d>-2-oxazoline (27963-97-9)

Guidance literature:

at 40 ℃; for 120h; pH=7; aq. phosphate buffer;

DOI:10.1002/anie.201001662

Reference yield:

2-amino-(1,2-dideoxy-α-D-ribofurano)<1,2-d>-2-oxazoline (27963-97-9) → (1R,2R)-1-(2-amino-1,3-oxazol-5-yl)propane-1,2,3-triol (1165930-35-7) + 4,5-dihydro-1,2-dideoxy-α-D-ribofuranoso[1,2-d]-1,3-oxazol-2-one (2508-81-8) + 2-amino-β-D-arabinofurano[1',2':4,5]-oxazoline (27963-98-0)

Guidance literature:

at 40 ℃; for 120h; pH=7; aq. phosphate buffer;

DOI:10.1002/anie.201001662

upstream raw materials:

(1R,2R)-1-(2-amino-1,3-oxazol-5-yl)propane-1,2,3-triol

2-amino-(1,2-dideoxy-α-D-ribofurano)<1,2-d>-2-oxazoline

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