1-AZETIDIN-3-YL-DIMETHYLAMINE HYDROCHLORIDE

Base Information

• Chemical Name: 1-AZETIDIN-3-YL-DIMETHYLAMINE HYDROCHLORIDE
• CAS No.: 935670-07-8
• Molecular Formula: C5H13ClN2
• Molecular Weight: 136.625
• Hs Code.: 2933990090
• Mol file: 935670-07-8.mol

Synonyms:3-(N,N-dimethylamino)-1-azetidine hydrochloride;azetidin-3-yldimethylamine hydrochloride;HT089;?N,N-dimethylazetidin-3-amine hydrochloride;3-Azetidinamine,N,N-dimethyl-,dihydrochloride;

Chemical Property of 1-AZETIDIN-3-YL-DIMETHYLAMINE HYDROCHLORIDE

Chemical Property:

• PSA: 15.27000
• LogP: 0.65060
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

N,N-Dimethylazetidin-3-amineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-AZETIDIN-3-YL-DIMETHYLAMINE HYDROCHLORIDE

There total 3 articles about 1-AZETIDIN-3-YL-DIMETHYLAMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl 3-(dimethylamino)azetidine-1-carboxylate (792970-55-9) → N,N-dimethylazetidin-3-amine monohydrochloride (935670-07-8,124668-49-1)

Guidance literature:

With hydrogenchloride; In diethyl ether; at 20 ℃; for 0.666667h;

Reference yield:

N,N-dimethylazetidine-3-amine → N,N-dimethylazetidin-3-amine monohydrochloride (935670-07-8,124668-49-1)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 5 h / 0 - 20 °C

2: hydrogenchloride / diethyl ether / 0.67 h / 20 °C

With hydrogenchloride; triethylamine; In diethyl ether; dichloromethane;

Reference yield:

3-(dimethylamino)-1-(diphenylmethyl)azetidine (55438-79-4) → N,N-dimethylazetidin-3-amine monohydrochloride (935670-07-8,124668-49-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: carbonochloridic acid 1-chloro-ethyl ester / 1,2-dichloro-ethane / 2 h / 100 °C

1.2: 2 h / 90 °C

2.1: triethylamine / dichloromethane / 5 h / 0 - 20 °C

3.1: hydrogenchloride / diethyl ether / 0.67 h / 20 °C

With hydrogenchloride; carbonochloridic acid 1-chloro-ethyl ester; triethylamine; In diethyl ether; dichloromethane; 1,2-dichloro-ethane;

upstream raw materials:

tert-butyl 3-(dimethylamino)azetidine-1-carboxylate

3-(dimethylamino)-1-(diphenylmethyl)azetidine

Refernces