Technology Process of 1H-INDAZOL-7-YL BORONIC ACID
There total 4 articles about 1H-INDAZOL-7-YL BORONIC ACID which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
water;
at 80 ℃;
for 20h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: hydrogen / palladium 10% on activated carbon / ethanol / 0.17 h / 20 °C
2.1: hydrogen bromide; sodium nitrite / water / 0.25 h / -10 - -5 °C
2.2: 2.25 h / -5 - 20 °C
3.1: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / dimethyl sulfoxide / 48 h / 100 °C
4.1: hydrogenchloride; water / 20 h / 80 °C
4.2: 20 °C / pH 6
With
hydrogenchloride; water; hydrogen bromide; hydrogen; potassium acetate; sodium nitrite;
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; palladium 10% on activated carbon;
In
ethanol; water; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydrogen bromide; sodium nitrite / water / 0.25 h / -10 - -5 °C
1.2: 2.25 h / -5 - 20 °C
2.1: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / dimethyl sulfoxide / 48 h / 100 °C
3.1: hydrogenchloride; water / 20 h / 80 °C
3.2: 20 °C / pH 6
With
hydrogenchloride; water; hydrogen bromide; potassium acetate; sodium nitrite;
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2;
In
water; dimethyl sulfoxide;
