Technology Process of 1-(2-(3,5-dichloro-2-(2-chlorophenoxy)phenoxy)ethyl)pyrimidine-2,4(1H,3H)-dione
There total 7 articles about 1-(2-(3,5-dichloro-2-(2-chlorophenoxy)phenoxy)ethyl)pyrimidine-2,4(1H,3H)-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonium hydroxide;
In
methanol;
at 20 ℃;
DOI:10.1021/jm201134m
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: boron tribromide / dichloromethane / -78 - 20 °C / Inert atmosphere
1.2: Inert atmosphere
2.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C
3.1: potassium carbonate / N,N-dimethyl-formamide / 20 - 60 °C
4.1: ammonium hydroxide / methanol / 20 °C
With
ammonium hydroxide; di-isopropyl azodicarboxylate; boron tribromide; potassium carbonate; triphenylphosphine;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
2.1: Mitsunobu reaction;
DOI:10.1021/jm201134m
- Guidance literature:
-
Multi-step reaction with 3 steps
1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 20 °C
2: potassium carbonate / N,N-dimethyl-formamide / 20 - 60 °C
3: ammonium hydroxide / methanol / 20 °C
With
ammonium hydroxide; di-isopropyl azodicarboxylate; potassium carbonate; triphenylphosphine;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
1: Mitsunobu reaction;
DOI:10.1021/jm201134m
