2-Chlorophenol

Base Information

• Chemical Name: 2-Chlorophenol
• CAS No.: 95-57-8
• Deprecated CAS: 1773488-59-7
• Molecular Formula: C6H5ClO
• Molecular Weight: 128.558
• Hs Code.: 2908.10
• European Community (EC) Number: 202-433-2,246-691-4
• ICSC Number: 0849
• NSC Number: 2870
• UN Number: 2021,2020
• UNII: K9KAV4K6BN
• DSSTox Substance ID: DTXSID5021544
• Nikkaji Number: J3.566A
• Wikipedia: 2-Chlorophenol
• Wikidata: Q176486
• Metabolomics Workbench ID: 52457
• ChEMBL ID: CHEMBL108877
• Mol file: 95-57-8.mol

Synonyms:2-chlorophenol;2-monochlorophenol;o-chlorophenol;o-monochlorophenol;ortho-chlorophenol;ortho-monochlorophenol

Chemical Property of 2-Chlorophenol

Chemical Property:

• Appearance/Colour: colourless to light brown liquid
• Vapor Pressure: 0.875mmHg at 25°C
• Melting Point: 8 °C(lit.)
• Refractive Index: n20/D 1.558(lit.)
• Boiling Point: 175 °C at 760 mmHg
• PKA: 8.50±0.10(Predicted)
• Flash Point: 63.9 °C
• PSA: 20.23000
• Density: 1.287 g/cm³
• LogP: 2.04560
• Water Solubility.: 28.5 g/L (20℃)
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 128.0028925
• Heavy Atom Count: 8
• Complexity: 74.9
• Transport DOT Label: Poison

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): Xn,N,T,F
• Hazard Codes: Xn:Harmful;;
• Statements: R20/21/22:; R51/53:
• Safety Statements: S28A:; S61:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Chlorophenols
• Canonical SMILES: C1=CC=C(C(=C1)O)Cl
• Inhalation Risk: No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
• Effects of Short Term Exposure: The substance is severely irritating to the eyes, skin and respiratory tract. Inhalation of the aerosol may cause lung oedema. The substance may cause effects on the central nervous system.
• General Description: o-Chlorophenol (also known as 2-chlorophenol) is a toxic chlorinated aromatic compound that poses environmental and health risks. Enzymatic degradation using horseradish peroxidase (HRP) immobilized on magnetic nanocomposites offers an efficient removal method, enhancing stability, reusability, and resistance to environmental fluctuations compared to free enzymes, making it suitable for wastewater treatment.

Technology Process of 2-Chlorophenol

There total 203 articles about 2-Chlorophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2,4-dibromo-6-chlorophenol (4526-56-1) → 2-monochlorophenol (95-57-8) + 2-bromo-6-chlorophenol (2040-88-2)

Guidance literature:

With copper; zinc; In sodium hydroxide; at 20 ℃; for 2h;

DOI:10.1002/(sici)1099-0690(199911)1999:11<2845::aid-ejoc2845>3.0.co;2-r

Reference yield: 37.0%

chlorobenzene (108-90-7) → 2-chloromaleic anhydride (96-02-6) + 2-monochlorophenol (95-57-8) + 4-chloro-phenol (106-48-9,82344-39-6) + chloro-p-hydroquinone (615-67-8)

Guidance literature:

With Fe₂(N,N-bis(pyridin-2-ylmethyl)prop-2-yn-1-amine)₂(μ₂-Cl)₂Cl₂; dihydrogen peroxide; In acetonitrile; at 70 ℃; for 2h;

DOI:10.1016/j.ica.2016.02.005

Reference yield: 18.4%

phenol (108-95-2,27073-41-2) → 2,6-Dichlorophenol (87-65-0) + 2-monochlorophenol (95-57-8) + 4-chloro-phenol (106-48-9,82344-39-6) + 2,4-dichlorophenol (120-83-2,40477-79-0) + 2,4,6-Trichlorophenol (88-06-2,67471-29-8)

Guidance literature:

With aluminium trichloride; diphenyl sulfide; chlorine; In neat (no solvent); at 35 ℃; for 1.5h; Product distribution; others 2-alkylphenols; var. chlorinating agent, temp., and time;

DOI:10.1021/jo00212a029

upstream raw materials:

2,2,6,6-tetrachlorocyclohexanol

3-chloro-4-hydroxybenzoic acid

3-Chloro-2-hydroxybenzoic acid

phenol-2-sulfonic acid

Downstream raw materials:

2-(2-chlorophenoxy)ethanol

2-chloro-6-(N-morpholinyl)methylphenol

2-Hydroxymethyl-2-<2-chlor-phenoxymethyl>-propandiol-(1,3)

1-(2-chloro-phenoxy)-3-piperidino-propan-2-ol

Refernces

Enzymatic removal of chlorophenols using horseradish peroxidase immobilized on superparamagnetic Fe₃O₄/graphene oxide nanocomposite

10.1016/S1872-2067(15)60856-7

This research aimed to develop an efficient method for the enzymatic removal of chlorophenols, which are harmful environmental pollutants, using horseradish peroxidase (HRP) immobilized on superparamagnetic Fe3O4/graphene oxide nanocomposites. The purpose was to leverage the high specificity and selectivity of enzymatic degradation while overcoming the poor stability and recovery challenges associated with free HRP. The study synthesized magnetic Fe3O4 nanoparticles deposited on graphene oxide sheets and used them to immobilize HRP. The immobilized HRP was then employed to remove 2-chlorophenol, 4-chlorophenol, and 2,4-dichlorophenol. The research concluded that the immobilized HRP demonstrated high stability, improved storage stability, and tolerance to pH and temperature changes compared to free HRP. It was also recoverable using an external magnetic field and retained significant activity over multiple cycles, showing potential for wastewater treatment applications.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 95-57-8 o-Chlorophenol

Send

Send

Metric Ton KG G Pound L ML

Send

Send