4-BROMOPHENYL TRIFLUOROMETHANESULFONATE

Base Information

• Chemical Name: 4-BROMOPHENYL TRIFLUOROMETHANESULFONATE
• CAS No.: 129112-25-0
• Molecular Formula: C7H4BrF3O3S
• Molecular Weight: 305.072
• Hs Code.: 2906299090
• Mol file: 129112-25-0.mol

Synonyms:4-Bromophenyl trifluoromethanesulphonate;4-Bromophenyl trifluoromethanesulphonate 97%;

Chemical Property of 4-BROMOPHENYL TRIFLUOROMETHANESULFONATE

Chemical Property:

• Refractive Index: 1.4770 to 1.4810
• Boiling Point: 15
• PSA: 51.75000
• LogP: 3.75830

Purity/Quality:

99% ^*data from raw suppliers

4-BromophenylTrifluoromethanesulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:
• Hazard Codes: R36/37/38:
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Bromophenyl trifluoromethanesulfonate is a useful research chemical.

Technology Process of 4-BROMOPHENYL TRIFLUOROMETHANESULFONATE

There total 4 articles about 4-BROMOPHENYL TRIFLUOROMETHANESULFONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trifluoromethylsulfonic anhydride (358-23-6) + 2-hydroxybromobenzene (95-56-7) → 2-(trifluoromethanesulfonyl)oxy-bromobenzene (129112-25-0)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 20 ℃; for 2h;

DOI:10.1021/acs.orglett.5b00844

Reference yield: 96.5%

2-hydroxybromobenzene (95-56-7) → 2-(trifluoromethanesulfonyl)oxy-bromobenzene (129112-25-0)

Guidance literature:

With pyridine; hydrogenchloride; trifluoromethanesulfonic acid anhydride; In dichloromethane;

Reference yield: 92.0%

N,N-phenylbistrifluoromethane-sulfonimide (37595-74-7) + 2-hydroxybromobenzene (95-56-7) → 2-(trifluoromethanesulfonyl)oxy-bromobenzene (129112-25-0)

Guidance literature:

With potassium hydrogen difluoride; water monomer; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 4h; Reagent/catalyst; chemoselective reaction;

DOI:10.1039/d1sc06267k

upstream raw materials:

trifluoromethylsulfonic anhydride

2-hydroxybromobenzene

sodium triflate

(2-bromophenyl)boronic acid

Downstream raw materials:

(9s,10s)-9,10-diphenyl-9,10-dihydro-9,10-epoxyanthracene

(2-(2-bromo-phenyl)ethynyl)triethylsilane

bis(3,5-di-tert-butyl-4-methoxyphenyl)-(2-bromophenyl)phosphine oxide

Refernces

• 1、 Uryu, Mizuho,Hiraga, Taito,Koga, Yoshito,Saito, Yutaro,Murakami, Kei,Itami, Kenichiro. "Synthesis of Polybenzoacenes: Annulative Dimerization of Phenylene Triflate by Twofold C?H Activation". . p. 6551 - 6554. Retrieved 2020.
• 2、 Cornella, Josep,Peciukenas, Vytautas,Planas, Oriol. "Bismuth-Catalyzed Oxidative Coupling of Arylboronic Acids with Triflate and Nonaflate Salts". supporting information. p. 11382 - 11387. Retrieved 2020/07/14.