1,2-Piperidinedicarboxylic acid, 1-(phenylmethyl) ester, (2S)-

Base Information

Chemical Name:1,2-Piperidinedicarboxylic acid, 1-(phenylmethyl) ester, (2S)-
CAS No.:71170-88-2
Molecular Formula:C₁₄H₁₇NO₄
Molecular Weight:263.293
Hs Code.:
DSSTox Substance ID:DTXSID00991484
Wikidata:Q72516407
Mol file:71170-88-2.mol

Synonyms:1,2-PIPERIDINEDICARBOXYLIC ACID, 1-(PHENYLMETHYL) ESTER, (2S)-;DTXSID00991484;AKOS015910678;1-[(Benzyloxy)carbonyl]piperidine-2-carboxylate

Suppliers and Price of 1,2-Piperidinedicarboxylic acid, 1-(phenylmethyl) ester, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
N-Carbobenzyloxy-2-piperidinecarboxylic acid 95+%
10 g
$ 30.00

SynChem
N-Carbobenzyloxy-2-piperidinecarboxylic acid 95+%
5 g
$ 20.00

AHH
1-(Carbobenzyloxy)-2-piperidinecarboxylicacid 97%
1000g
$ 355.00

Total 56 raw suppliers

Chemical Property of 1,2-Piperidinedicarboxylic acid, 1-(phenylmethyl) ester, (2S)-

Chemical Property:

Vapor Pressure:1.16E-08mmHg at 25°C
Melting Point:80-83 °C(lit.)
Boiling Point:443.9°C at 760 mmHg
Flash Point:222.3°C
PSA：66.84000
LogP:2.20020
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:262.10793299
Heavy Atom Count:19
Complexity:320

Purity/Quality:

98% ^*data from raw suppliers

N-Carbobenzyloxy-2-piperidinecarboxylic acid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C(C1)C(=O)[O-])C(=O)OCC2=CC=CC=C2
Isomeric SMILES:C1CCN([C@@H](C1)C(=O)[O-])C(=O)OCC2=CC=CC=C2

Technology Process of 1,2-Piperidinedicarboxylic acid, 1-(phenylmethyl) ester, (2S)-

There total 31 articles about 1,2-Piperidinedicarboxylic acid, 1-(phenylmethyl) ester, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: 1723-00-8,83680-83-5
(R)-(+)-pipecolic acid

: 28697-07-6,28697-09-8,28697-11-2,71170-88-2
(R)-1-((benzyloxy)carbonyl)piperidine-2-carboxylic acid

Guidance literature:: With sodium hydroxide; In water; for 1h; Ambient temperature;

Reference yield: 60.0%

: (R)-benzyl 2-((S)-1,2-dihydroxyethyl)piperidine-1-carboxylate

: 28697-07-6,28697-09-8,28697-11-2,71170-88-2
(R)-1-((benzyloxy)carbonyl)piperidine-2-carboxylic acid

Guidance literature:: With sodium periodate; ruthenium(III) chloride hexahydrate; In tetrachloromethane; water; acetonitrile; at 20 ℃; for 1h;
DOI:10.1016/j.tetasy.2014.08.001

Reference yield: 52.0%

: benzyl-(2S)-2-[(1S)-1,2-dihydroxyethyl]piperidine-1-carboxylate

: 28697-07-6,28697-09-8,28697-11-2,71170-88-2
(R)-1-((benzyloxy)carbonyl)piperidine-2-carboxylic acid

Guidance literature:: With ruthenium trichloride; sodium periodate; water; In tetrachloromethane; acetonitrile; at 20 ℃; for 2h;
DOI:10.1016/0957-4166(95)00382-7