2-(Trifluoromethoxy)anisole

Base Information

Chemical Name:2-(Trifluoromethoxy)anisole
CAS No.:261952-22-1
Molecular Formula:C8H7F3O2
Molecular Weight:192.14
Hs Code.:2909309090
DSSTox Substance ID:DTXSID10380406
Nikkaji Number:J1.699.078G
Wikidata:Q72511242
Mol file:261952-22-1.mol

Synonyms:2-(Trifluoromethoxy)anisole;1-methoxy-2-(trifluoromethoxy)benzene;261952-22-1;2-Trifluoromethoxyanisole;SCHEMBL625622;DTXSID10380406;MFCD01631503;AKOS015889473;AM61435;PS-8334;Benzene, 1-methoxy-2-(trifluoromethoxy)-;A5202;CS-0087899;FT-0651606;E89585

Suppliers and Price of 2-(Trifluoromethoxy)anisole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Trifluoromethoxy)anisole
500mg
$ 90.00

Crysdot
1-Methoxy-2-(trifluoromethoxy)benzene 95+%
100g
$ 414.00

Chemenu
2-(Trifluoromethoxy)anisole 95%
100g
$ 391.00

Apolloscientific
2-(Trifluoromethoxy)anisole 97%
25g
$ 172.00

Apolloscientific
2-(Trifluoromethoxy)anisole 97%
5g
$ 53.00

Apolloscientific
2-(Trifluoromethoxy)anisole 97%
1g
$ 32.00

American Custom Chemicals Corporation
2-(TRIFLUOROMETHOXY)ANISOLE 95.00%
1G
$ 644.49

American Custom Chemicals Corporation
2-(TRIFLUOROMETHOXY)ANISOLE 95.00%
5G
$ 905.52

Alichem
2-(Trifluoromethoxy)anisole
1g
$ 1475.10

Alichem
2-(Trifluoromethoxy)anisole
500mg
$ 831.30

Total 39 raw suppliers

Chemical Property of 2-(Trifluoromethoxy)anisole

Chemical Property:

Boiling Point:145 ºC
Flash Point:47 ºC
PSA：18.46000
Density:1.249
LogP:2.59380
Storage Temp.:2-8°C
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:192.03981395
Heavy Atom Count:13
Complexity:158

Purity/Quality:

98% ^*data from raw suppliers

2-(Trifluoromethoxy)anisole ^*data from reagent suppliers

Safty Information:

Pictogram(s): F
Hazard Codes:F

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1OC(F)(F)F

Technology Process of 2-(Trifluoromethoxy)anisole

There total 8 articles about 2-(Trifluoromethoxy)anisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 32858-93-8
2-(trifluoromethoxy)phenol

: 74-88-4
methyl iodide

: 261952-22-1
1-methoxy-2-(trifluoromethoxy)benzene

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 1h; Inert atmosphere;

Reference yield: 77.0%

: 86487-17-4
2-tri-n-butylstannylanisole

: 96898-10-1
tris(dimethylamino)sulfonium trifluoromethoxide

: 261952-22-1
1-methoxy-2-(trifluoromethoxy)benzene

Guidance literature:: 2-tri-n-butylstannylanisole; tris(dimethylamino)sulfonium trifluoromethoxide; With trifluoromethyl trifluoromethanesulfonate; sodium hydrogencarbonate; In tetrahydrofuran; at -30 ℃; Inert atmosphere;

With silver(I) hexafluorophosphate; 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(hexafluorophosphate); In tetrahydrofuran; acetone; at -30 - 23 ℃; Inert atmosphere; Darkness;
DOI:10.1021/ja204861a