C₉H₁₀FNO₅S*ClH

Base Information

• Chemical Name: C₉H₁₀FNO₅S*ClH
• CAS No.: 2227199-79-1
• Molecular Formula: C₉H₁₀FNO₅S*ClH
• Molecular Weight: 299.707
• Mol file: 2227199-79-1.mol

Synonyms:

Chemical Property of C₉H₁₀FNO₅S*ClH

Chemical Property:

Purity/Quality:

99%min. ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₉H₁₀FNO₅S*ClH

There total 5 articles about C₉H₁₀FNO₅S*ClH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

Boc-Tyr-OSO2F → fluorosulfate-L-tyrosine hydrochloride salt (2227199-79-1)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane;

DOI:10.1021/jacs.8b01087

Reference yield:

C14H18FNO7S → C9H10FNO5S*ClH (2227199-79-1)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃;

DOI:10.1021/jacs.0c02956

Reference yield:

Boc-Tyr-OH (3978-80-1) → fluorosulfate-L-tyrosine hydrochloride salt (2227199-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: fluorosulfonyl fluoride; sodium tetraborate decahydrate / dichloromethane / 4 h

2: hydrogenchloride / 1,4-dioxane / 20 °C

With hydrogenchloride; fluorosulfonyl fluoride; sodium tetraborate decahydrate; In 1,4-dioxane; dichloromethane;

DOI:10.1021/jacs.0c02956

upstream raw materials:

L-tyrosine

Boc-Tyr-OH

N-(tert-butoxycarbonyl)-D-tyrosine