Technology Process of (E)-6-(3-carboxy-2-butenyl)-2,3,5-trimethyl-1,4-benzoquinone
There total 5 articles about (E)-6-(3-carboxy-2-butenyl)-2,3,5-trimethyl-1,4-benzoquinone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) BF3/Et2O, 2.) FeCl3 / 1.) dioxane, RT, 90 min, 2.) dioxane/aq. methanol, RT, 10 min
2: 85 percent / Zn / pyridine / 0.5 h / Ambient temperature
3: 81 percent / OsO4, NaIO4 / dioxane; H2O / 1 h / Ambient temperature
4: 92 percent / benzene / 1 h / Heating
5: 1.) 10percent KOH, Na2S2O4, 2.) FeCl3 / 1.) acetone, reflux, 8 h, 2.) aq. MeOH, 1 h
With
potassium hydroxide; sodium periodate; osmium(VIII) oxide; sodium dithionite; diethyl ether; boron trifluoride; iron(III) chloride; zinc;
In
1,4-dioxane; pyridine; water; benzene;
DOI:10.1248/cpb.30.2797
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 92 percent / benzene / 1 h / Heating
2: 1.) 10percent KOH, Na2S2O4, 2.) FeCl3 / 1.) acetone, reflux, 8 h, 2.) aq. MeOH, 1 h
With
potassium hydroxide; sodium dithionite; iron(III) chloride;
In
benzene;
DOI:10.1248/cpb.30.2797
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 85 percent / Zn / pyridine / 0.5 h / Ambient temperature
2: 81 percent / OsO4, NaIO4 / dioxane; H2O / 1 h / Ambient temperature
3: 92 percent / benzene / 1 h / Heating
4: 1.) 10percent KOH, Na2S2O4, 2.) FeCl3 / 1.) acetone, reflux, 8 h, 2.) aq. MeOH, 1 h
With
potassium hydroxide; sodium periodate; osmium(VIII) oxide; sodium dithionite; iron(III) chloride; zinc;
In
1,4-dioxane; pyridine; water; benzene;
DOI:10.1248/cpb.30.2797
