3-Chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

Base Information

Chemical Name:3-Chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS No.:1083168-91-5
Molecular Formula:C12H17BClNO3
Molecular Weight:269.53228
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90694497
Wikidata:Q82623610
Mol file:1083168-91-5.mol

Synonyms:1083168-91-5;3-chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;5-Chloro-6-methoxypyridine-3-boronic acid pinacol ester;3-CHLORO-2-METHOXYPYRIDINE-5-BORONIC ACID PINACOL ESTER;(5-CHLORO-6-METHOXYPYRIDIN-3-YL)BORONIC ACID PINACOL ESTER;3-Chloro-2-methoxypyridine-5-boronicacidpinacolester;SCHEMBL3673238;DTXSID90694497;ZHWIZWNYOSGXSR-UHFFFAOYSA-N;MFCD08063054;AKOS015950179;MB05256;AS-42788;CS-0174397;FT-0734264;EN300-7407081;A849306;J-512194;Z2044773084;3-CHLORO-2-METHOXY-5-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE;3-Chloro-2-methoxy-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine;3-chloro-2-methoxy-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine

Suppliers and Price of 3-Chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Chloro-2-methoxypyridine-5-boronicAcidPinacolEster
500mg
$ 185.00

TRC
3-Chloro-2-methoxypyridine-5-boronicAcidPinacolEster
250mg
$ 120.00

Crysdot
3-Chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 95+%
5g
$ 452.00

AOBChem
5-Chloro-6-methoxypyridine-3-boronicacidpinacolester 97%
500mg
$ 84.00

American Custom Chemicals Corporation
5-CHLORO-6-METHOXYPYRIDINE-3-BORONIC ACID PINACOL ESTER 95.00%
1G
$ 357.00

Alichem
3-Chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
5g
$ 758.16

Alfa Aesar
5-Chloro-6-methoxypyridine-3-boronic acid pinacol ester, 96%
250mg
$ 66.80

Alfa Aesar
5-Chloro-6-methoxypyridine-3-boronic acid pinacol ester, 96%
1g
$ 219.00

AK Scientific
3-Chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
1g
$ 237.00

AccelPharmtech
5-Chloro-6-methoxypyridine-3-boronicacidpinacolester 97.00%
25G
$ 13300.00

Total 24 raw suppliers

Chemical Property of 3-Chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

Chemical Property:

PSA：40.58000
LogP:2.04280
Storage Temp.:2-8°C
Water Solubility.:Slightly soluble in water.
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:269.0990013
Heavy Atom Count:18
Complexity:298

Purity/Quality:

97% ^*data from raw suppliers

3-Chloro-2-methoxypyridine-5-boronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC(=C(N=C2)OC)Cl
Uses 5-Chloro-6-methoxypyridine-3-boronic acid pinacol ester is used as pharmaceutical intermediate.

Technology Process of 3-Chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

There total 1 articles about 3-Chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 848366-28-9
5-bromo-3-chloro-2-methoxypyridine

: 73183-34-3
bis(pinacol)diborane

: 1083168-91-5
3-chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In N,N-dimethyl-formamide; at 80 ℃;

Reference yield:

: 1083168-91-5
3-chloro-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

: N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)-4-chloro-2-methoxybenzenesulfonamide

: 4-chloro-N-((1S,2R)-2-(3-(5-chloro-6-methoxypyridin-3-yl)-6-fluoro-2-methylphenyl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)-2-methoxybenzenesulfonamide

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sodium carbonate; In 1,4-dioxane; water; at 100 ℃; for 1h;