2--4,7-diphenyl-pyrido<2,3-d>pyrimidin

Base Information

• Chemical Name: 2--4,7-diphenyl-pyrido<2,3-d>pyrimidin
• CAS No.: 85852-65-9
• Molecular Formula: C₂₃H₂₂N₄O₂
• Molecular Weight: 386.453
• Mol file: 85852-65-9.mol

Synonyms:

Chemical Property of 2--4,7-diphenyl-pyrido<2,3-d>pyrimidin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2--4,7-diphenyl-pyrido<2,3-d>pyrimidin

There total 3 articles about 2--4,7-diphenyl-pyrido<2,3-d>pyrimidin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.8%

2-Chlor-4,7-diphenyl-pyrido<2,3-d>pyrimidin (85852-60-4) + 2,2'-iminobis[ethanol] (111-42-2) → 2--4,7-diphenyl-pyrido<2,3-d>pyrimidin (85852-65-9)

Guidance literature:

In ethanol; for 3h; Heating;

DOI:10.1002/ardp.19833160411

Reference yield:

4,7-Diphenyl-pyrido<2,3-d>pyrimidin-2(1H)-on (85852-58-0) → 2--4,7-diphenyl-pyrido<2,3-d>pyrimidin (85852-65-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 63.8 percent / PCl₅, POCl₃ / 0.33 h / Heating

2: 90.8 percent / ethanol / 3 h / Heating

With phosphorus pentachloride; trichlorophosphate; In ethanol;

DOI:10.1002/ardp.19833160411

Reference yield:

2-Amino-6-phenyl-pyrid-3-yl-phenyl-keton (81471-37-6) → 2--4,7-diphenyl-pyrido<2,3-d>pyrimidin (85852-65-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 66 percent / 2 h / 200 - 210 °C

2: 63.8 percent / PCl₅, POCl₃ / 0.33 h / Heating

3: 90.8 percent / ethanol / 3 h / Heating

With phosphorus pentachloride; trichlorophosphate; In ethanol;

DOI:10.1002/ardp.19833160411

upstream raw materials:

2-Chlor-4,7-diphenyl-pyrido<2,3-d>pyrimidin

2,2'-iminobis[ethanol]

4,7-Diphenyl-pyrido<2,3-d>pyrimidin-2(1H)-on

2-Amino-6-phenyl-pyrid-3-yl-phenyl-keton