1-(Benzyloxy)-3,5-difluorobenzene

Base Information

Chemical Name:1-(Benzyloxy)-3,5-difluorobenzene
CAS No.:176175-97-6
Molecular Formula:C13H10F2O
Molecular Weight:220.219
Hs Code.:2909309090
DSSTox Substance ID:DTXSID70471364
Nikkaji Number:J1.987.382J
Mol file:176175-97-6.mol

Synonyms:1-(benzyloxy)-3,5-difluorobenzene;176175-97-6;1-Benzyloxy-3,5-difluorobenzene;1,3-difluoro-5-phenylmethoxybenzene;SCHEMBL5042093;DTXSID70471364;AMY26000;BHA17597;MFCD18072457;AKOS016008178;AS-41288;1-(Benzyloxy)-3,5-difluorobenzene, 98%;Benzene, 1,3-difluoro-5-(phenylmethoxy)-;A3912;FT-0715886

Suppliers and Price of 1-(Benzyloxy)-3,5-difluorobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(Benzyloxy)-3,5-difluorobenzene
100mg
$ 60.00

Labseeker
1-(Benzyloxy)-3,5-difluorobenzene 98
10g
$ 1083.00

Crysdot
1-(Benzyloxy)-3,5-difluorobenzene 97%
5g
$ 460.00

AOBChem
1-Benzyloxy-3,5-difluorobenzene 97%
10g
$ 520.00

AOBChem
1-Benzyloxy-3,5-difluorobenzene 97%
25g
$ 1021.00

American Custom Chemicals Corporation
1-(BENZYLOXY)-3,5-DIFLUOROBENZENE 95.00%
5MG
$ 497.05

Alichem
1-(Benzyloxy)-3,5-difluorobenzene
10g
$ 793.94

Alichem
1-(Benzyloxy)-3,5-difluorobenzene
5g
$ 503.99

Alichem
1-(Benzyloxy)-3,5-difluorobenzene
1g
$ 162.68

Total 14 raw suppliers

Chemical Property of 1-(Benzyloxy)-3,5-difluorobenzene

Chemical Property:

Boiling Point:266.001 °C at 760 mmHg
Flash Point:121.942 °C
PSA：9.23000
Density:1.206 g/cm³
LogP:3.54380
Storage Temp.:2-8°C
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:220.06997126
Heavy Atom Count:16
Complexity:194

Purity/Quality:

97% ^*data from raw suppliers

1-(Benzyloxy)-3,5-difluorobenzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC(=CC(=C2)F)F

Technology Process of 1-(Benzyloxy)-3,5-difluorobenzene

There total 3 articles about 1-(Benzyloxy)-3,5-difluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 2713-34-0
3,5-difluorophenol

: 100-44-7
benzyl chloride

: 176175-97-6
1-benzyloxy-3,5-difluorobenzene

Guidance literature:: With sodium hydroxide; In ethanol; at 100 ℃; for 1h;
DOI:10.1016/j.tetlet.2003.10.109

Reference yield: 74.55%

: 2713-34-0
3,5-difluorophenol

: 100-39-0
benzyl bromide

: 176175-97-6
1-benzyloxy-3,5-difluorobenzene

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 85 ℃; for 12h;

Reference yield: 73.0%

: 372-38-3
1,3,5-trifluorobenzene

: 100-51-6,185532-71-2
benzyl alcohol

: 176175-97-6
1-benzyloxy-3,5-difluorobenzene

Guidance literature:: benzyl alcohol; With sodium hydride; In 1-methyl-pyrrolidin-2-one; mineral oil; at 0 ℃; for 1h;

1,3,5-trifluorobenzene; In 1-methyl-pyrrolidin-2-one; mineral oil; at 0 - 20 ℃; regioselective reaction;
DOI:10.1246/cl.2011.744