Oxazolo[5,4-c]pyridine-2(1h)-thione

Base Information

Chemical Name:Oxazolo[5,4-c]pyridine-2(1h)-thione
CAS No.:169205-98-5
Molecular Formula:C6H4N2OS
Molecular Weight:152.17
Hs Code.:
DSSTox Substance ID:DTXSID901293679
Mol file:169205-98-5.mol

Synonyms:oxazolo[5,4-c]pyridine-2(1h)-thione;169205-98-5;1H-[1,3]OXAZOLO[5,4-C]PYRIDINE-2-THIONE;OXAZOLO[5,4-C]PYRIDINE-2-THIOL;SCHEMBL6213165;DTXSID901293679;AB65956

Suppliers and Price of Oxazolo[5,4-c]pyridine-2(1h)-thione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Oxazolo[5,4-c]pyridine-2(1h)-thione

Chemical Property:

Appearance/Colour:Light yellow solid
Melting Point:>290 °C
Boiling Point:284.1±32.0 °C(Predicted)
PKA:9.68±0.20(Predicted)
PSA：73.91000
Density:1.53±0.1 g/cm3(Predicted)
LogP:1.88540
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:152.00443393
Heavy Atom Count:10
Complexity:162

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=CC2=C1NC(=S)O2

Technology Process of Oxazolo[5,4-c]pyridine-2(1h)-thione

There total 5 articles about Oxazolo[5,4-c]pyridine-2(1h)-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 52334-53-9
4-amino-3-hydroxy pyridine

: 140-89-6
potassium ethyl xanthogenate

: 169205-98-5
2-Mercaptooxazolo<5,4-c>pyridine

Guidance literature:: In ethanol; for 18h; Heating;
DOI:10.1021/jo00122a073

Reference yield: 47.0%

: 169205-98-5
2-Mercaptooxazolo<5,4-c>pyridine

Guidance literature:: In ethanol; for 24h; Reflux;

Reference yield:

: 70298-89-4
4-N-pivaloylaminopyridine

: 169205-98-5
2-Mercaptooxazolo<5,4-c>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: n-BuLi; trimethylborate; H₂O₂

2: HCl; NaOH / H₂O

3: 79 percent / ethanol / 18 h / Heating

With hydrogenchloride; sodium hydroxide; n-butyllithium; Trimethyl borate; dihydrogen peroxide; In ethanol; water;
DOI:10.1016/j.ejmech.2004.09.010