1,1,7,7-Tetramethyljulolidine

Base Information

• Chemical Name: 1,1,7,7-Tetramethyljulolidine
• CAS No.: 325722-28-9
• Molecular Formula: C16H23N
• Molecular Weight: 229.36
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID60464407
• Nikkaji Number: J1.853.380D
• Wikidata: Q72507661
• Mol file: 325722-28-9.mol

Synonyms:325722-28-9;1,1,7,7-Tetramethyljulolidine;1,1,7,7-tetramethyl-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline;1,1,7,7-Tetramethyl-1,2,3,5,6,7-hexahydro-pyrido[3,2,1-ij]quinoline;1,1,7,7-TETRAMETHYL-2,3,6,7-TETRAHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE;4,4,10,10-tetramethyl-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene;SCHEMBL7644556;DTXSID60464407;BCP04331;AKOS015842262;SB66763;CS-0451040;FT-0660663;4,4,10,10-tetramethyl-1-azatricyclo[7.3.1.0^{5,13]trideca-5(13),6,8-triene

Chemical Property of 1,1,7,7-Tetramethyljulolidine

Chemical Property:

• Appearance/Colour: White Crystals
• Vapor Pressure: 0.000958mmHg at 25°C
• Refractive Index: 1.566
• Boiling Point: 303 °C at 760 mmHg
• PKA: 6.68±0.60(Predicted)
• Flash Point: 125 °C
• PSA: 3.24000
• Density: 1.02 g/cm³
• LogP: 3.92060
• Storage Temp.: 2-8°C
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 229.183049738
• Heavy Atom Count: 17
• Complexity: 277

Purity/Quality:

98%min ^*data from raw suppliers

1,1,7,7-Tetramethyl-1,2,3,5,6,7-hexahydro-pyrido[3,2,1-ij]quinoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CCN2CCC(C3=CC=CC1=C32)(C)C)C

Technology Process of 1,1,7,7-Tetramethyljulolidine

There total 4 articles about 1,1,7,7-Tetramethyljulolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

N,N-bis(3-methylbut-2-ene-1-yl)aniline (36127-33-0) → 1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline (325722-28-9) + 2-(4',4'-dimethyl-1'-phenyl-3'-piperidyl)-2-propene-1-sulfonic acid

Guidance literature:

With methanesulfonic acid; sulfuric acid; at 0 ℃; for 1h;

DOI:10.1016/S0040-4039(02)02506-6

Reference yield: 17.0%

N,N-bis(3-methylbut-2-ene-1-yl)aniline (36127-33-0) → 1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline (325722-28-9)

Guidance literature:

With sulfuric acid; at 0 - 20 ℃; for 24h;

Reference yield:

aniline (62-53-3) → 1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline (325722-28-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: calcium carbonate / N,N-dimethyl-formamide / 0.5 h / 65 °C

1.2: 0.67 h / 80 °C

2.1: sulfuric acid / 24 h / 0 - 20 °C

With sulfuric acid; calcium carbonate; In N,N-dimethyl-formamide;

upstream raw materials:

N,N-bis(3-methylbut-2-ene-1-yl)aniline

aniline

3,3-dimethyl-allyl chloride

Downstream raw materials:

1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-carboxaldehyde

Refernces

• 1、 -. "NOVEL CATHODE BUFFER LAYER MATERIAL AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING SAME". Paragraph 0167; 0169-0170. . Retrieved 2021/02/05.