1-Isomangostin hydrate

Base Information

• Chemical Name: 1-Isomangostin hydrate
• CAS No.: 26063-95-6
• Molecular Formula: C24H28O7
• Molecular Weight: 428.5
• Mol file: 26063-95-6.mol

Synonyms:1-isomangostin hydrate;

Chemical Property of 1-Isomangostin hydrate

Chemical Property:

• PSA: 109.36000
• LogP: 4.17310

Purity/Quality:

98%min ^*data from raw suppliers

1-Isomangostinhydrate ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Isomangostin hydrate

There total 7 articles about 1-Isomangostin hydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1-isomangostin (19275-44-6) → 1-isomangostin hydrate (26063-95-6)

Guidance literature:

With toluene-4-sulfonic acid; acetic acid; In methanol; at 20 ℃; for 20h;

DOI:10.1016/j.bmcl.2020.127494

Reference yield: 63.0%

α-mangostin (6147-11-1) → 1-isomangostin hydrate (26063-95-6) + 3-isomangostin (19275-46-8)

Guidance literature:

With sulfuric acid; In toluene; at 40 ℃; for 4h; Inert atmosphere; Molecular sieve;

DOI:10.1080/14786419.2014.986729

Reference yield: 29.0%

α-mangostin (6147-11-1) → 1-isomangostin hydrate (26063-95-6) + 1-isomangostin (19275-44-6)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at 0 - 20 ℃; for 14h; Reagent/catalyst;

DOI:10.1080/14786419.2014.986729

upstream raw materials:

formic acid

α-mangostin

1-isomangostin

Refernces

• 1、 Chi, Xiao-Qian,Zi, Cheng-Ting,Li, Hong-Mei,Yang, Liu,Lv, Yong-Feng,Li, Jin-Yu,Hou, Bo,Ren, Fu-Cai,Hu, Jiang-Miao,Zhou, Jun. "Design, synthesis and structure-activity relationships of mangostin analogs as cytotoxic agents". . p. 41377 - 41388. Retrieved 2019/01/03.
• 2、 Ren, Yulin,Matthew, Susan,Lantvit, Daniel D.,Ninh, Tran Ngoc,Chai, Heebyung,Fuchs, James R.,Soejarto, Djaja D.,De Blanco, Esperanza J. Carcache,Swanson, Steven M.,Kinghorn, A. Douglas. "Cytotoxic and NF-κB inhibitory constituents of the stems of Cratoxylum cochinchinense and their semisynthetic analogues". experimental part. p. 1117 - 1125. Retrieved 2011/07/30.