4-carbamoylphenylglyoxylic acid

Base Information

• Chemical Name: 4-carbamoylphenylglyoxylic acid
• CAS No.: 76590-51-7
• Molecular Formula: C₉H₇NO₄
• Molecular Weight: 193.159
• Mol file: 76590-51-7.mol

Synonyms:

Chemical Property of 4-carbamoylphenylglyoxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-carbamoylphenylglyoxylic acid

There total 2 articles about 4-carbamoylphenylglyoxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-cyanophenyl methyl ketone (1443-80-7) → 4-carbamoylphenylglyoxylic acid (76590-51-7)

Guidance literature:

Multi-step reaction with 2 steps

1: selenium dioxide / pyridine / Heating

2: conc. H₂SO₄ / 0.75 h

With selenium(IV) oxide; sulfuric acid; In pyridine;

DOI:10.1021/jm00136a009

Reference yield:

2-(4-cyanophenyl)-2-oxoacetic acid (76590-50-6) → 4-carbamoylphenylglyoxylic acid (76590-51-7)

Guidance literature:

With sulfuric acid; for 0.75h; Yield given;

DOI:10.1021/jm00136a009

Reference yield:

4-carbamoylphenylglyoxylic acid (76590-51-7) + diaminomaleonitrile (1187-42-4) → 4-(5,6-Dicyano-3-hydroxy-pyrazin-2-yl)-benzamide

Guidance literature:

With hydrogenchloride; In methanol; at 25 ℃; for 2h; Yield given;

upstream raw materials:

2-(4-cyanophenyl)-2-oxoacetic acid

4-cyanophenyl methyl ketone