4-methoxycarbonyl-2-nitrobenzyl 2,3-di-O-acetyl-4,6-O-<1,1,3,3-tetra(2-propyl)-disiloxan-1,3-yl>-β-D-glucopyranoside

Base Information

• Chemical Name: 4-methoxycarbonyl-2-nitrobenzyl 2,3-di-O-acetyl-4,6-O-<1,1,3,3-tetra(2-propyl)-disiloxan-1,3-yl>-β-D-glucopyranoside
• CAS No.: 126412-64-4
• Molecular Formula: C₃₁H₄₉NO₁₃Si₂
• Molecular Weight: 699.9
• Mol file: 126412-64-4.mol

Synonyms:

Chemical Property of 4-methoxycarbonyl-2-nitrobenzyl 2,3-di-O-acetyl-4,6-O-<1,1,3,3-tetra(2-propyl)-disiloxan-1,3-yl>-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methoxycarbonyl-2-nitrobenzyl 2,3-di-O-acetyl-4,6-O-<1,1,3,3-tetra(2-propyl)-disiloxan-1,3-yl>-β-D-glucopyranoside

There total 4 articles about 4-methoxycarbonyl-2-nitrobenzyl 2,3-di-O-acetyl-4,6-O-<1,1,3,3-tetra(2-propyl)-disiloxan-1,3-yl>-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-(hydroxymethyl)-3-nitrobenzoate (89950-93-6) → 4-methoxycarbonyl-2-nitrobenzyl 2,3-di-O-acetyl-4,6-O-<1,1,3,3-tetra(2-propyl)-disiloxan-1,3-yl>-β-D-glucopyranoside (126412-64-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) molecular sieve, 2.) boron trifluoride ethyl etherate / 1.) dichloromethane, 1 h, 2.) 2 h

2: 98 percent / sodium methoxide / methanol; CH₂Cl₂ / 0.25 h

With molecular sieve; boron trifluoride diethyl etherate; sodium methylate; In methanol; dichloromethane;

DOI:10.1016/0008-6215(89)85131-6

Reference yield:

4-methoxycarbonyl-2-nitrobenzyl-2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside (89950-94-7) → 4-methoxycarbonyl-2-nitrobenzyl 2,3-di-O-acetyl-4,6-O-<1,1,3,3-tetra(2-propyl)-disiloxan-1,3-yl>-β-D-glucopyranoside (126412-64-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / sodium methoxide / methanol; CH₂Cl₂ / 0.25 h

With sodium methylate; In methanol; dichloromethane;

DOI:10.1016/0008-6215(89)85131-6

Reference yield:

2,3,4,6-tetra-O-acetyl-1-fluoro-α-D-glucopyranose (439-03-2,439-04-3,439-05-4,2823-44-1,2823-46-3,3934-29-0,4163-44-4,4163-45-5,20409-31-8,23235-96-3,51897-75-7,51897-76-8,51897-77-9,57573-38-3,62561-28-8,126641-47-2) → 4-methoxycarbonyl-2-nitrobenzyl 2,3-di-O-acetyl-4,6-O-<1,1,3,3-tetra(2-propyl)-disiloxan-1,3-yl>-β-D-glucopyranoside (126412-64-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) molecular sieve, 2.) boron trifluoride ethyl etherate / 1.) dichloromethane, 1 h, 2.) 2 h

2: 98 percent / sodium methoxide / methanol; CH₂Cl₂ / 0.25 h

With molecular sieve; boron trifluoride diethyl etherate; sodium methylate; In methanol; dichloromethane;

DOI:10.1016/0008-6215(89)85131-6

upstream raw materials:

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

acetic anhydride

4-methoxycarbonyl-2-nitrobenzyl β-D-glucopyranoside

methyl 4-(hydroxymethyl)-3-nitrobenzoate

Downstream raw materials:

4-methoxycarbonyl-2-nitrobenzyl 2,3-di-O-acetyl-4,6-di-O-(3,4,6-tri-O-acetyl-α-D-glucopyranosyl)-β-D-glucopyranoside

4-methoxycarbonyl-2-nitrobenzyl 2,3-di-O-acetyl-4-O-(2,4,6-tri-O-acetyl-α-D-glucopyranosyl)-β-D-glucopyranoside

C₂₇H₃₉NO₂₀

4-carboxy-2-nitrobenzyl 4,6-di-O-α-D-glucopyranosyl-β-D-glucopyranoside