[(2-Methoxybenzylidene)amino]benzene

Base Information

• Chemical Name: [(2-Methoxybenzylidene)amino]benzene
• CAS No.: 3369-37-7
• Molecular Formula: C14H13NO
• Molecular Weight: 211.263
• Hs Code.: 2925290090
• Mol file: 3369-37-7.mol

Synonyms:[(2-Methoxybenzylidene)amino]benzene;N-(2-Methoxybenzylidene)aniline;N-[(2-Methoxyphenyl)methylene]benzenamine

Chemical Property of [(2-Methoxybenzylidene)amino]benzene

Chemical Property:

• Melting Point: 39-40 °C
• Boiling Point: 347.7±25.0 °C(Predicted)
• PKA: 3.11±0.50(Predicted)
• PSA: 21.59000
• Density: 0.99±0.1 g/cm3(Predicted)
• LogP: 3.44580

Purity/Quality:

99% ^*data from raw suppliers

N-(2-METHOXYBENZYLIDENE)ANILINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [(2-Methoxybenzylidene)amino]benzene

There total 13 articles about [(2-Methoxybenzylidene)amino]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

aniline (62-53-3) + ortho-anisaldehyde (135-02-4) → N-(o-methoxybenzylidene)aniline (3369-37-7)

Guidance literature:

In chloroform; for 16h; Reflux;

DOI:10.1021/acs.orglett.1c03908

Reference yield: 94.0%

(2-methoxyphenyl)methanol (612-16-8) + aniline (62-53-3) → N-(o-methoxybenzylidene)aniline (3369-37-7)

Guidance literature:

With C₃₀H₂₄AgBr₄N₈⁽¹⁺⁾*AgBr₂^(1-); N-benzyl-trimethylammonium hydroxide; In toluene; at 20 ℃; for 12h; Molecular sieve; Schlenk technique;

DOI:10.1021/ol501353q

Reference yield: 92.0%

(2-methoxyphenyl)methanol (612-16-8) + nitrobenzene (98-95-3,26969-40-4) → N-(o-methoxybenzylidene)aniline (3369-37-7)

Guidance literature:

With ruthenium trichloride; potassium carbonate; at 130 ℃; for 24h; Inert atmosphere; Green chemistry;

upstream raw materials:

aniline

ortho-anisaldehyde

N-phenylsalicylaldimine

methyl iodide

Downstream raw materials:

4t-(2-methoxy-phenyl)-1,3r-diphenyl-azetidin-2-one

salicylaldehyde

ortho-anisaldehyde

3-methyl-5-<2-(2-methoxyphenyl)ethenyl>isoxazole