5-(4'-tert-butylthiophenyl)-2,2'-bithiophene

Base Information

• Chemical Name: 5-(4'-tert-butylthiophenyl)-2,2'-bithiophene
• CAS No.: 756899-89-5
• Molecular Formula: C₁₈H₁₈S₃
• Molecular Weight: 330.539
• Mol file: 756899-89-5.mol

Synonyms:

Chemical Property of 5-(4'-tert-butylthiophenyl)-2,2'-bithiophene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(4'-tert-butylthiophenyl)-2,2'-bithiophene

There total 4 articles about 5-(4'-tert-butylthiophenyl)-2,2'-bithiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

para-bromobenzenethiol (106-53-6) → 5-(4'-tert-butylthiophenyl)-2,2'-bithiophene (756899-89-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 100 percent / aluminum chloride / 1 h / 20 °C

2: tetrakis(triphenylphosphine)palladium⁽⁰⁾ / toluene / Heating

3: N-bromosuccinimide / CHCl₃; acetic acid / 6 h

4: sodium carbonate; tetrakis(triphenylphosphine)palladium⁽⁰⁾ / ethanol / Heating

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; aluminium trichloride; sodium carbonate; In ethanol; chloroform; acetic acid; toluene; 2: Stille cross-coupling / 4: Suzuki cross-coupling;

DOI:10.1002/hc.10224

Reference yield:

tert-butyl 4-bromophenyl sulfide (25752-90-3) → 5-(4'-tert-butylthiophenyl)-2,2'-bithiophene (756899-89-5)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrakis(triphenylphosphine)palladium⁽⁰⁾ / toluene / Heating

2: N-bromosuccinimide / CHCl₃; acetic acid / 6 h

3: sodium carbonate; tetrakis(triphenylphosphine)palladium⁽⁰⁾ / ethanol / Heating

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; chloroform; acetic acid; toluene; 1: Stille cross-coupling / 3: Suzuki cross-coupling;

DOI:10.1002/hc.10224

Reference yield:

2-(4-tert-butylsulfanylphenyl)thiophene (756899-88-4) → 5-(4'-tert-butylthiophenyl)-2,2'-bithiophene (756899-89-5)

Guidance literature:

Multi-step reaction with 2 steps

1: N-bromosuccinimide / CHCl₃; acetic acid / 6 h

2: sodium carbonate; tetrakis(triphenylphosphine)palladium⁽⁰⁾ / ethanol / Heating

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; chloroform; acetic acid; 2: Suzuki cross-coupling;

DOI:10.1002/hc.10224

upstream raw materials:

thiophene boronic acid

5-bromo-2-(4'-tert-buylthiophenyl)thiophene

tert-butyl 4-bromophenyl sulfide

para-bromobenzenethiol