8-hydrazinylquinoline hydrochloride

Base Information

• Chemical Name: 8-hydrazinylquinoline hydrochloride
• CAS No.: 14148-42-6
• Molecular Formula: C9H9N3
• Molecular Weight: 159.191
• Hs Code.: 2933990090
• Mol file: 14148-42-6.mol

Synonyms:[8]Chinolyl-hydrazin;8-hydrazino-quinoline;8-hydrazinylquinoline;8-quinolylhydrazine;Quinoline,8-hydrazino;

Chemical Property of 8-hydrazinylquinoline hydrochloride

Chemical Property:

• PSA: 50.94000
• LogP: 2.29370

Purity/Quality:

97% ^*data from raw suppliers

Quinolin-8-yl-hydrazine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-hydrazinylquinoline hydrochloride

There total 7 articles about 8-hydrazinylquinoline hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.6%

8-quinolinol (148-24-3,24804-14-6) → 8-hydrazinoquinoline (14148-42-6)

Guidance literature:

With hydrazine hydrate; for 120h; Reflux;

DOI:10.1016/j.poly.2017.04.030

Reference yield: 87.0%

2‐[2‐(diphenylmethylidene)hydrazin‐1‐yl]‐4‐methoxypyridine (913839-70-0) → 8-hydrazinoquinoline (14148-42-6)

Guidance literature:

With hydrogenchloride; water; In toluene; at 90 ℃; for 15h; Inert atmosphere;

DOI:10.1021/jacs.7b02020

Reference yield: 40.0%

8-amino quinoline (578-66-5) → 8-hydrazinoquinoline (14148-42-6)

Guidance literature:

8-amino quinoline; With hydrogenchloride; In water; at 0 ℃; for 1.5h;

With hydrogenchloride; sodium nitrite; In water; Cooling with ice;

With hydrogenchloride; tin(ll) chloride; In water; at 8 ℃; Cooling with ice;

upstream raw materials:

8-quinolinol

8-amino quinoline

8-bromoquinoline

benzophenone hydrazone

Downstream raw materials:

2,2-bis(diphenylphosphino)-1-(quinolyl-8)-hydrazine

(S)-2-(1,3-dioxoisoindolin-2-yl)-3-phenyl-N-(quinolin-8-yl)propanamide

3-Phenyl-1-(quinolin-8-ylamino)-1,3-dihydro-indol-2-one

N-acetyl-8-(β-benziloylhydrazino)quinolinium chloride