4-Amino-1-benzyl-3-methylpiperidine

Base Information

• Chemical Name: 4-Amino-1-benzyl-3-methylpiperidine
• CAS No.: 82378-86-7
• Molecular Formula: C13H20N2
• Molecular Weight: 204.315
• Hs Code.: 2933399090
• Mol file: 82378-86-7.mol

Synonyms:4-Amino-1-benzyl-3-methylpiperidine;4-PiperidinaMine, 3-Methyl-1-(phenylMethyl)-;1-benzyl-3-Methylpiperidin-4-aMine;1-Benzyl-3-methylpiperidin-4-ylamine

Chemical Property of 4-Amino-1-benzyl-3-methylpiperidine

Chemical Property:

• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.542
• Boiling Point: 291.136 °C at 760 mmHg
• Flash Point: 120.985 °C
• PSA: 29.26000
• Density: 1.005 g/cm³
• LogP: 2.49390
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1-benzyl-3-methylpiperidin-4-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Amino-1-benzyl-3-methylpiperidine

There total 2 articles about 4-Amino-1-benzyl-3-methylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-benzyl-3-methyl-piperidin-4-one oxime → 1-benzyl-3-methyl-4-aminopiperidine (82378-86-7,88915-34-8,88915-33-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 25 - 50 ℃;

Reference yield:

1-Benzyl-3-methyl-4-piperidon (34737-89-8) → 1-benzyl-3-methyl-4-aminopiperidine (82378-86-7,88915-34-8,88915-33-7)

Guidance literature:

With ammonium acetate; sodium cyanoborohydride; In methanol; water;

Reference yield: 89.0%

1-benzyl-3-methyl-4-aminopiperidine (82378-86-7,88915-34-8,88915-33-7) + (4-propionyl-phenoxy)-acetic acid (6501-31-1) → C24H30N2O3

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃;

upstream raw materials:

1-Benzyl-3-methyl-4-piperidon