N-((1-pyridin-2-yl)benzylidene)-N'-[2-(4-[2-[((1-pyridin-2-yl)benzylidene)amino]ethyl]piperazin-1-yl)-ethyl]amine

Base Information

• Chemical Name: N-((1-pyridin-2-yl)benzylidene)-N'-[2-(4-[2-[((1-pyridin-2-yl)benzylidene)amino]ethyl]piperazin-1-yl)-ethyl]amine
• CAS No.: 959850-48-7
• Molecular Formula: C₃₂H₃₄N₆
• Molecular Weight: 502.662
• Mol file: 959850-48-7.mol

Synonyms:

Chemical Property of N-((1-pyridin-2-yl)benzylidene)-N'-[2-(4-[2-[((1-pyridin-2-yl)benzylidene)amino]ethyl]piperazin-1-yl)-ethyl]amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-((1-pyridin-2-yl)benzylidene)-N'-[2-(4-[2-[((1-pyridin-2-yl)benzylidene)amino]ethyl]piperazin-1-yl)-ethyl]amine

There total 1 articles about N-((1-pyridin-2-yl)benzylidene)-N'-[2-(4-[2-[((1-pyridin-2-yl)benzylidene)amino]ethyl]piperazin-1-yl)-ethyl]amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.1%

1,4-bis(2-aminoethyl)piperazine (6531-38-0) + phenyl(pyridin-2-yl)methanone (91-02-1) → N-((1-pyridin-2-yl)benzylidene)-N'-[2-(4-[2-[((1-pyridin-2-yl)benzylidene)amino]ethyl]piperazin-1-yl)-ethyl]amine (959850-48-7)

Guidance literature:

for 7h; Reflux;

DOI:10.1016/j.poly.2011.05.007

Reference yield: 84.0%

N-(1-pyridin-2-yl-phenylidene)-N'-[2-({2-[(1-pyridin-2-yl-phenylidene)amino]ethyl}amino)ethyl]ethane-1,2-diamine (518294-06-9) + ammonium thiocyanate + nickel(II) perchlorate hexahydrate + N-((1-pyridin-2-yl)benzylidene)-N'-[2-(4-[2-[((1-pyridin-2-yl)benzylidene)amino]ethyl]piperazin-1-yl)-ethyl]amine (959850-48-7) → nickel(II) (N-(1-pyridin-2-yl-phenylidene)-N'-[2-([2-[(1-pyridin-2-yl phenylidene)amino]ethyl]amino)ethyl]ethane-1,2-diamine) Ni2(N-(1-pyridin-2-ylphenylidene)-N'-[2([2-[(1-pyridin-2-ylphenylidene)amino]ethyl]piperazine-1-yl)ethyl]amine)(thiocyanate)6 (1318684-04-6)

Guidance literature:

In methanol; MeOH soln. of Ni(ClO4)2*6H2O and NH4SCN added to MeOH soln. of ligand, in other pot Ni(ClO4)2*6H2O added to MeOH soln. of ligand, soln. mixed, slowly evapd. for 1 wk; filtered; elem. anal.;

DOI:10.1016/j.poly.2011.05.007

Reference yield: 75.0%

sodium azide + N-((1-pyridin-2-yl)benzylidene)-N'-[2-(4-[2-[((1-pyridin-2-yl)benzylidene)amino]ethyl]piperazin-1-yl)-ethyl]amine (959850-48-7) + lead(II) acetate trihydrate (6080-56-4) → Pb2(N-((1-pyridin-2-yl)benzylidene)-N'-[2-(4-[2-[((1-pyridin-2-yl)benzylidene)amino]ethyl]piperazin-1-yl)-ethyl]amine)(azide)4 (1220187-94-9)

Guidance literature:

In methanol; soln. of ligand in MeOH added dropwise to soln. of Pb(CH3CO2)2*3H2O in MeOH, soln. of NaN3 in MeOH added; soln. filtered, filtrate allowed to evap. in air for a few d, crystals filtered off, washed with toluene, dried under vac. over silica; elem. anal.;

DOI:10.1016/j.molstruc.2009.12.015

upstream raw materials:

1,4-bis(2-aminoethyl)piperazine

phenyl(pyridin-2-yl)methanone

Downstream raw materials:

Cd₂(N-(1-pyridin-2-ylbenzylidene)-N-[2-(4-(2-[(1-pyridin-2-ylbenzylidene)amino]ethyl)piperazin-1-yl)ethyl]amine)(H₂O)2(N₃)4

Pb₂(N-((1-pyridin-2-yl)benzylidene)-N'-[2-(4-[2-[((1-pyridin-2-yl)benzylidene)amino]ethyl]piperazin-1-yl)-ethyl]amine)(azide)4

Pb₂(N-((1-pyridin-2-yl)benzylidene)-N'-[2-(4-[2-[((1-pyridin-2-yl)benzylidene)amino]ethyl]piperazin-1-yl)-ethyl]amine)(isothiocyanate)4

nickel(II) (N-(1-pyridin-2-yl-phenylidene)-N'-[2-([2-[(1-pyridin-2-yl phenylidene)amino]ethyl]amino)ethyl]ethane-1,2-diamine) Ni₂(N-(1-pyridin-2-ylphenylidene)-N'-[2([2-[(1-pyridin-2-ylphenylidene)amino]ethyl]piperazine-1-yl)ethyl]amine)(thiocyanate)6

Refernces