C₂₆H₄₀BrN₃O₆S

Base Information

• Chemical Name: C₂₆H₄₀BrN₃O₆S
• CAS No.: 1378243-23-2
• Molecular Formula: C₂₆H₄₀BrN₃O₆S
• Molecular Weight: 602.59
• Mol file: 1378243-23-2.mol

Synonyms:

Chemical Property of C₂₆H₄₀BrN₃O₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₄₀BrN₃O₆S

There total 4 articles about C₂₆H₄₀BrN₃O₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S)-2-(2-(tert-butoxycarbonylamino)-4-(methylthio)butanamido)-4-methylpentanoic acid (33014-87-8) + (S)-2-amino-3-(4-bromophenyl)propionic acid methyl ester hydrochloride (99359-32-7) → C26H40BrN3O6S (1378243-23-2)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; Cooling with ice;

DOI:10.1002/psc.2414

Reference yield:

methyl (L)-leucinate hydrochloride (7517-19-3) → C26H40BrN3O6S (1378243-23-2)

Guidance literature:

Multi-step reaction with 3 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Cooling with ice

2: water; sodium hydroxide / methanol / 0 - 20 °C

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Cooling with ice

With water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; dichloromethane;

DOI:10.1002/psc.2414

Reference yield:

N-tert-butoxycarbonyl-L-methionine (2488-15-5) → C26H40BrN3O6S (1378243-23-2)

Guidance literature:

Multi-step reaction with 3 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Cooling with ice

2: water; sodium hydroxide / methanol / 0 - 20 °C

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Cooling with ice

With water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; dichloromethane;

DOI:10.1002/psc.2414

upstream raw materials:

N-tert-butoxycarbonyl-L-methionine

methyl (L)-leucinate hydrochloride

(2S)-2-(2-(tert-butoxycarbonylamino)-4-(methylthio)butanamido)-4-methylpentanoic acid

(S)-2-amino-3-(4-bromophenyl)propionic acid methyl ester hydrochloride

Downstream raw materials:

C₂₂H₃₂BrN₃O₅S