2,5-Difluoro-4-iodopyridine

Base Information

Chemical Name:2,5-Difluoro-4-iodopyridine
CAS No.:1017793-20-2
Molecular Formula:C5H2F2IN
Molecular Weight:240.979
Hs Code.:2933399090
DSSTox Substance ID:DTXSID40692903
Wikidata:Q72463093
Mol file:1017793-20-2.mol

Synonyms:2,5-DIFLUORO-4-IODOPYRIDINE;1017793-20-2;2,5-difluoro-4-iodo-pyridine;MFCD11040606;Pyridine,2,5-difluoro-4-iodo-;Difluoro-4-iodopyridine;SCHEMBL2016623;DTXSID40692903;OBVRKNZQNKGNTQ-UHFFFAOYSA-N;Pyridine, 2,5-difluoro-4-iodo-;AMY12480;BCP14926;BBL102442;STL556244;AKOS015853520;PB47990;AC-25104;DS-16884;SY030496;CS-0005562;FT-0682849;P17560;EN300-7364184

Suppliers and Price of 2,5-Difluoro-4-iodopyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,5-Difluoro-4-iodopyridine
100mg
$ 75.00

SynQuest Laboratories
2,5-Difluoro-4-iodopyridine
5 g
$ 296.00

SynQuest Laboratories
2,5-Difluoro-4-iodopyridine
1 g
$ 136.00

Matrix Scientific
2,5-Difluoro-4-iodopyridine 97%
1g
$ 29.00

Matrix Scientific
2,5-Difluoro-4-iodopyridine 97%
5g
$ 89.00

Crysdot
2,5-Difluoro-4-iodopyridine 98%
100g
$ 891.00

Crysdot
2,5-Difluoro-4-iodopyridine 98%
25g
$ 277.00

ChemScene
2,5-Difluoro-4-iodopyridine 98.51%
10g
$ 133.00

ChemScene
2,5-Difluoro-4-iodopyridine 98.51%
5g
$ 82.00

ChemScene
2,5-Difluoro-4-iodopyridine 98.51%
25g
$ 266.00

Total 57 raw suppliers

Chemical Property of 2,5-Difluoro-4-iodopyridine

Chemical Property:

Boiling Point:209.7 °C at 760 mmHg
PKA:-4.24±0.18(Predicted)
Flash Point:80.6 °C
PSA：12.89000
Density:2.129 g/cm³
LogP:1.96440
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:240.92000
Heavy Atom Count:9
Complexity:101

Purity/Quality:

98%, ^*data from raw suppliers

2,5-Difluoro-4-iodopyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CN=C1F)F)I

Technology Process of 2,5-Difluoro-4-iodopyridine

There total 2 articles about 2,5-Difluoro-4-iodopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 84476-99-3
2,5-difluoropyridine

: 1017793-20-2
preparation of 2,5-difluoro-4-iodopyridine

Guidance literature:: 2,5-difluoropyridine; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 - -68 ℃; for 1.5h;

With iodine; In tetrahydrofuran; hexane; at -75 - -60 ℃; for 2h;
DOI:10.1021/acs.oprd.0c00397

Reference yield: 48.0%

: 108-18-9
diisopropylamine

: 84476-99-3
2,5-difluoropyridine

: 1017793-20-2
preparation of 2,5-difluoro-4-iodopyridine

Guidance literature:: diisopropylamine; With n-butyllithium; In tetrahydrofuran; hexane; at -20 ℃; for 0.666667h;

2,5-difluoropyridine; In tetrahydrofuran; hexane; at -78 ℃; for 4.5h;

With iodine; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

Reference yield: 92.0%

: 1017793-20-2
preparation of 2,5-difluoro-4-iodopyridine

: 1765-93-1
4-fluoroboronic acid

: 2,5-difluoro-4-(4-fluorophenyl)pyridine

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; In 1,2-dimethoxyethane; water; at 100 ℃;