10-propargyl-10-carbomethoxy-4-deoxy-4-amino-10-deazapteroic acid methyl ester hydrobromide salt

Base Information

Chemical Name:10-propargyl-10-carbomethoxy-4-deoxy-4-amino-10-deazapteroic acid methyl ester hydrobromide salt
CAS No.:1548618-47-8
Molecular Formula:BrH*C₂₁H₂₀N₆O₄
Molecular Weight:501.34
Hs Code.:

Synonyms:

Suppliers and Price of 10-propargyl-10-carbomethoxy-4-deoxy-4-amino-10-deazapteroic acid methyl ester hydrobromide salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
6-Pteridinepropanoicacid,2,4-diamino-α-[4-(methoxycarbonyl)phenyl]-α-2-propyn-1-yl-,methylester,hydrobromide
100mg
$ 450.00

ChemScene
6-Pteridinepropanoicacid,2,4-diamino-α-[4-(methoxycarbonyl)phenyl]-α-2-propyn-1-yl-,methylester,hydrobromide
250mg
$ 750.00

ChemScene
6-Pteridinepropanoicacid,2,4-diamino-α-[4-(methoxycarbonyl)phenyl]-α-2-propyn-1-yl-,methylester,hydrobromide
1g
$ 1500.00

Chemenu
Methyl4-(2-((2,4-diaminopteridin-6-yl)methyl)-1-methoxy-1-oxopent-4-yn-2-yl)benzoatehydrobromide 95%+
250mg
$ 1268.00

Chemenu
Methyl4-(2-((2,4-diaminopteridin-6-yl)methyl)-1-methoxy-1-oxopent-4-yn-2-yl)benzoatehydrobromide 95%+
100mg
$ 702.00

Total 7 raw suppliers

Chemical Property of 10-propargyl-10-carbomethoxy-4-deoxy-4-amino-10-deazapteroic acid methyl ester hydrobromide salt

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

6-Pteridinepropanoicacid,2,4-diamino-α-[4-(methoxycarbonyl)phenyl]-α-2-propyn-1-yl-,methylester,hydrobromide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 10-propargyl-10-carbomethoxy-4-deoxy-4-amino-10-deazapteroic acid methyl ester hydrobromide salt

There total 4 articles about 10-propargyl-10-carbomethoxy-4-deoxy-4-amino-10-deazapteroic acid methyl ester hydrobromide salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.7%

: 52853-40-4
6-bromomethyl-2,4-diaminopteridine hydrobromide

: 146464-90-6
α-propargylhomoterephthalic acid dimethyl ester

: 1548618-47-8
10-propargyl-10-carbomethoxy-4-deoxy-4-amino-10-deazapteroic acid methyl ester hydrobromide salt

Guidance literature:: 6-bromomethyl-2,4-diaminopteridine hydrobromide; α-propargylhomoterephthalic acid dimethyl ester; With sodium hydride; In N,N-dimethyl acetamide; at -20 - -10 ℃;

With hydrogen bromide; In methanol; dichloromethane; water; isopropyl alcohol; at 0 - 5 ℃; Concentration;

Reference yield:

: 146464-91-7
methyl-4-(2-((2,4-diaminopteridin-6-yl)methyl)-1-methoxy-1-oxopent-4-yn-2-yl)benzoate

: 1548618-47-8
10-propargyl-10-carbomethoxy-4-deoxy-4-amino-10-deazapteroic acid methyl ester hydrobromide salt

Guidance literature:: With hydrogen bromide; In methanol; dichloromethane; water; isopropyl alcohol; at 0 - 5 ℃; Concentration;

Reference yield:

: 52787-14-1
methyl 4-(2-methoxy-2-oxoethyl)benzoate

: 1548618-47-8
10-propargyl-10-carbomethoxy-4-deoxy-4-amino-10-deazapteroic acid methyl ester hydrobromide salt

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate; tetra-(n-butyl)ammonium iodide / N,N-dimethyl acetamide / 25 - 30 °C

2.1: sodium hydride / N,N-dimethyl acetamide / -20 - -10 °C

2.2: 0 - 5 °C

With tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; In N,N-dimethyl acetamide;