Quinoline, 6-bromo-4-(4-pyridazinyl)-

Base Information

Chemical Name:Quinoline, 6-bromo-4-(4-pyridazinyl)-
CAS No.:1086063-18-4
Molecular Formula:C13H8BrN3
Molecular Weight:286.131
Hs Code.:
Mol file:1086063-18-4.mol

Synonyms:6-bromoquinolone;6-bromo-4-morpholinoquinazoline;6-bromoquinolin-4(1H)-one;6-Brom-3-(2-pyridyl)-cumarin;6-bromo-3-(2-pyridyl)coumarin;6-BROMO-3-(PYRIDIN-2-YL)-CHROMEN-2-ONE;6-bromo-4-morpholin-4-yl-quinazoline;6-bromo-4-oxo-4H-quinoline;6-bromo-4-(pyridazin-4-yl)quinoline;COUMARIN,6-BROMO-3-(2-PYRIDYL);6-bromo-1H-quinolin-4-one;

Suppliers and Price of Quinoline, 6-bromo-4-(4-pyridazinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Bromo-4-(pyridazin-4-yl)quinoline 97%
1g
$ 447.00

Chemenu
6-bromo-4-(pyridazin-4-yl)quinoline 97%
1g
$ 422.00

Alichem
6-Bromo-4-(pyridazin-4-yl)quinoline
1g
$ 400.00

Total 19 raw suppliers

Chemical Property of Quinoline, 6-bromo-4-(4-pyridazinyl)-

Chemical Property:

Boiling Point:487.9±45.0 °C(Predicted)
PKA:2.15±0.49(Predicted)
PSA：38.67000
Density:1.549±0.06 g/cm3(Predicted)
LogP:3.45430

Purity/Quality:

98%min ^*data from raw suppliers

6-Bromo-4-(pyridazin-4-yl)quinoline 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Quinoline, 6-bromo-4-(4-pyridazinyl)-

There total 5 articles about Quinoline, 6-bromo-4-(4-pyridazinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 927801-23-8
6-bromo-4-iodoquinoline

: 194865-89-9
4-(tributylstannanyl)pyridazine

: 1086063-18-4
6-bromo-4-(pyridazin-4-yl)quinoline

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; Reflux;
DOI:10.1016/j.bmcl.2011.12.136

Reference yield:

: 65340-70-7
6-bromo-4-chloroquinoline

: 1086063-18-4
6-bromo-4-(pyridazin-4-yl)quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / tetrahydrofuran; diethyl ether / 0.5 h / 20 °C

2: sodium iodide / propiononitrile / 96 h / Reflux

3: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / Reflux

With hydrogenchloride; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sodium iodide; In tetrahydrofuran; 1,4-dioxane; diethyl ether; propiononitrile;
DOI:10.1016/j.bmcl.2011.12.136

Reference yield:

: 1086062-75-0
6-bromo-4-chloroquinoline hydrochloride

: 1086063-18-4
6-bromo-4-(pyridazin-4-yl)quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium iodide / propiononitrile / 96 h / Reflux

2: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / Reflux

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sodium iodide; In 1,4-dioxane; propiononitrile;
DOI:10.1016/j.bmcl.2011.12.136