A 70360

Base Information

• Chemical Name: A 70360
• CAS No.: 130465-42-8
• Molecular Formula: C₁₆H₁₇NO₃*ClH
• Molecular Weight: 307.777
• Mol file: 130465-42-8.mol

Synonyms:

Chemical Property of A 70360

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of A 70360

There total 17 articles about A 70360 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-<2',3'-(cyclohexylidenedioxy)phenyl>-1-phenylethanone (130378-87-9) → A 68930 hydrochloride (130465-39-3,130465-41-7,130465-42-8,134731-69-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 75 percent / (-)-B-chlorodiisopinocampheyborane

2: BF₃*Et₂O

3: LiN₃ / dimethylformamide

4: lithium aluminum hydride (LAH) / diethyl ether

5: HCl / ethanol

With hydrogenchloride; lithium aluminium tetrahydride; lithium azide; boron trifluoride diethyl etherate; (-)-diisopinocamphenylborane chloride; In diethyl ether; ethanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00173a005

Reference yield:

C20H22O3 (134647-81-7) → A 68930 hydrochloride (130465-39-3,130465-41-7,130465-42-8,134731-69-4)

Guidance literature:

Multi-step reaction with 6 steps

1: pyridinium chlorochromate (PCC)

2: 75 percent / (-)-B-chlorodiisopinocampheyborane

3: BF₃*Et₂O

4: LiN₃ / dimethylformamide

5: lithium aluminum hydride (LAH) / diethyl ether

6: HCl / ethanol

With hydrogenchloride; lithium aluminium tetrahydride; lithium azide; boron trifluoride diethyl etherate; (-)-diisopinocamphenylborane chloride; pyridinium chlorochromate; In diethyl ether; ethanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00173a005

Reference yield:

spiro[benzo[d][1,3]dioxole-2,1'-cyclohexane] (182-55-8) → A 68930 hydrochloride (130465-39-3,130465-41-7,130465-42-8,134731-69-4)

Guidance literature:

Multi-step reaction with 7 steps

1: 1.) n-BuLi / 1.) THF

2: pyridinium chlorochromate (PCC)

3: 75 percent / (-)-B-chlorodiisopinocampheyborane

4: BF₃*Et₂O

5: LiN₃ / dimethylformamide

6: lithium aluminum hydride (LAH) / diethyl ether

7: HCl / ethanol

With hydrogenchloride; lithium aluminium tetrahydride; n-butyllithium; lithium azide; boron trifluoride diethyl etherate; (-)-diisopinocamphenylborane chloride; pyridinium chlorochromate; In diethyl ether; ethanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00173a005

upstream raw materials:

C₂₂H₂₅NO₃

styrene oxide

2-<2',3'-(cyclohexylidenedioxy)phenyl>-1-phenylethanone

C₂₀H₂₂O₃