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Usage

Uses

Used in Chemical Research:
Spiro[1,3-benzodioxole-2,1'-cyclohexane] serves as a valuable compound in chemical research for its unique structural and chemical properties, which can be explored for novel reactions and synthesis pathways.
Used in Pharmaceutical Manufacturing:
In the pharmaceutical industry, spiro[1,3-benzodioxole-2,1'-cyclohexane] may be utilized as an intermediate or a building block in the synthesis of complex organic molecules, potentially leading to the development of new drugs.
Used in Industrial Settings:
spiro[1,3-benzodioxole-2,1'-cyclohexane]'s stability and properties make it a candidate for use in various industrial applications, where it could be employed in the formulation of materials with specific characteristics required for certain processes or products.
As the specific applications of spiro[1,3-benzodioxole-2,1'-cyclohexane] are not widely documented, ongoing research and development are necessary to uncover its full potential across different sectors.

Upstream product

• 108-94-1 cyclohexanone 
• 120-80-9 benzene-1,2-diol 
• 220350-18-5 (3R,4S)-4-((S)-3-Benzyl-1-oxa-4-aza-spiro[4.5]decane-4-sulfonyl)-3-trifluoromethyl-cyclohexanone 
• 119657-54-4 cis-2-(2-hydroxyphenoxy)-1-mesyloxycyclohexane 

Downstream Products

• 67874-24-2 6'-methyl-spiro[cyclohexane-1,2'-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazole] 
• 7573-08-2 3-Dodecyl-brenzcatechin 
• 134456-07-8 2-cyclohexyl-1-spiro<1,3-benzodioxole-2,1'-cyclohexane>-2-ethanol 
• 134647-81-7 C₂₀H₂₂O₃ 
• 134647-71-5 C₂₂H₂₆O₄ 
• 87275-36-3 2-(1-cyclohexenoxy)-1-acetoxybenzene 
• 87275-35-2 2-(α-bromocyclohexoxy)-1-acetoxybenzene 
• 87275-34-1 2-(α-hydroxycyclohexoxy)-1-acetoxybenzene 
• 26419-58-9 5-acetylspiro<1,3-benzodioxa-2,1'-cyclohexane> 
• 17497-53-9 1-iodo-1-cyclohexene 
• 635-67-6 dimethyl phthalate 
• 29443-47-8 1,1-diiodocyclohexane 
• 72712-21-1 3,4-diacetoxyacetophenone 
• 64179-40-4 5-nitrospiro<1,3-benzodioxole-2,1'-cyclohexane> 

Relevant academic research and scientific papers

Copper-Catalyzed Asymmetric Three-Component Borylstannation: Enantioselective Formation of C-Sn Bond

In summary, a first copper-catalyzed synthesis of α-aryl-β-borylstannane compounds was accomplished through three-component borylstannation of aryl-substituted alkenes. In the exploration of an asymmetric variant, chiral sulfinylphosphine ligands proved a

PROCESS FOR PRODUCTION OF HYDROXYTYROSOL USING ORGANOMETALLIC COMPOUNDS

Disclosed is a process for the production of a 4-(2-hydroxyalkyl)-1,2-benzenediol, comprising the steps of (a) providing protected 1,2-benzenediol having the 1,2-hydroxyl groups protected, (b) halogenating the protected 1,2-benzenediol to obtain a protected 4-halo-1,2-benzenediol having the 1,2-hydroxyl groups protected, (c) reacting, in the presence of a metal or organometallic compound, the protected 4-halo-1,2-benzenediol to protected 4-(2-hydroxyalkyl)-1,2-benzenediol having the 1,2-hydroxyl groups protected, and (d) deprotecting the protected 4-(2-hydroxyalkyl)-1,2-benzenediol to obtain the 4-(2-hydroxyalkyl)-1,2-benzenediol. Also disclosed is the use of 1,2-benzenediol for the production of hydroxytyrosol.

Cu(II)-impregnated sulfated MCM-41: An efficient and convenient protocol for the synthesis of 1,3-benzodioxoles

An efficient synthesis of 1,3-benzodioxoles was achieved from catechol with different aldehydes and ketones using Cu(II) impregnated sulfated MCM-41 as an efficient and reusable catalyst. Copyright Taylor & Francis Group, LLC.

Microwave-assisted synthesis of 1,3-benzodioxole derivatives from catechol and ketones or aldehydes

An efficient synthetic procedure for the preparation of a diverse library of 1,3-benzodioxoles was developed by applying controlled microwave heating in comparison with currently available conventional heating. Reactions were completed in less than 3 h. The isolation of product is simple, the isolated yields are good to excellent, and this method is applicable to large scale production.

Diallylation of 2,2-dialkylbenzodioxoles from TiCl4-mediated allylsilane reaction

Reaction of aliphatic ketones with catechol afforded 2,2-dialkylbenzodioxoles. Treatment of these benzodioxoles with allyltrimethylsilane in the presence of titanium tetrachloride led to 4,4-dialkylhepta-1,6-dienes resulting from a diallylation process. R

NEW PHARMACEUTICAL COMPOUNDS

Compounds of formula (I), wherein R1-R4, X, Y and Z are as defined in claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors.

(4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS

The present invention comprises (4-Piperidinyl)-1H-2-Benzopyran derivatives useful as antipsychotic agents, their intermediates, pharmaceutical compositions and methods of making these compounds. These compounds are useful in treating psychosis.

An efficient and convenient method for preparation of 2,2-disubstituted and 2-monosubstituted 1,3-benzodioxoles from ketones and aldehydes with catechol catalysed by zro2/so42-

The title compounds have been synthesised by reaction of catechol with ketones and aldehydes catalysed by ZrO2/SO42- solid superacid in high yields. Ketones gave better yields than aldehydes.

(4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS

The present invention comprises (4-Piperidinyl)-1H-2-Benzopyran derivatives useful as antipsychotic agents, their intermediates, pharmaceutical compositions and methods of making these compounds. These compounds are useful in treating psychosis.

Asymmetric Diels-Alder reaction of optically active 3-(3,3,3- trifluoropropenylsulfonyl)oxazolidine: Synthesis of (8R)8-trifluoromethyl-2- oxa-6-thia-5-azatricyclo[5.2.2.01,5]-undecane-6,6-dioxide

Asymmetric Diels-Alder reaction of optically active 3-(3,3,3- trifluoropropenylsulfonyl)-1,3-oxazolidine (1) with several dienes gave adducts regio- and stereoselectively in 69 - 78% de. Acetalization of 2- methoxybutadiene adduct with catechol gave tricy