4-chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine

Base Information

Chemical Name:4-chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine
CAS No.:881844-11-7
Molecular Formula:C14H12ClN3O
Molecular Weight:273.722
Hs Code.:
Mol file:881844-11-7.mol

Synonyms:1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile,4-chloro-1-(phenylsulfonyl);4-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile;4-chloro-1-(p-methoxybenzyl)-1H-imidazo[4,5-c]pyridine;

Suppliers and Price of 4-chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
4-Chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine 95+%
1g
$ 958.00

Chemenu
4-Chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine 95+%
250mg
$ 559.00

Chemenu
4-Chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine 95+%
100mg
$ 279.00

Total 15 raw suppliers

Chemical Property of 4-chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine

Chemical Property:

Boiling Point:483.0±55.0 °C(Predicted)
PKA:3.11±0.30(Predicted)
PSA：39.94000
Density:1.31±0.1 g/cm3(Predicted)
LogP:3.14160

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine

There total 11 articles about 4-chloro-1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

: 2770-01-6
4-chloro-1H-imidazo[4,5-c]pyridine

: 824-94-2
p-methoxybenzyl chloride

: 881844-11-7
4-chloro-1-(p-methoxybenzyl)-1H-imidazo[4,5-c]pyridine

: 4-chloro-3-(4-methoxybenzyl)-3H-imidazo[4,5-c]pyridine

Guidance literature:: 4-chloro-1H-imidazo[4,5-c]pyridine; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h; Inert atmosphere;

p-methoxybenzyl chloride; In N,N-dimethyl-formamide; at 20 ℃; for 72h; Inert atmosphere;
DOI:10.1016/j.bmc.2016.09.055

Reference yield:

: 39217-08-8
2-chloropyridine-3,4-diamine

: 881844-11-7
4-chloro-1-(p-methoxybenzyl)-1H-imidazo[4,5-c]pyridine

: 4-chloro-3-(4-methoxybenzyl)-3H-imidazo[4,5-c]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / water / 20 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 0.33 h / 20 °C / Inert atmosphere

2.2: 72 h / 20 °C / Inert atmosphere

With hydrogenchloride; potassium carbonate; In water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2016.09.055

Reference yield:

: 881844-09-3
2-chloro-N-(4-methoxybenzyl)-3-nitropyridin-4-amine

: 881844-11-7
4-chloro-1-(p-methoxybenzyl)-1H-imidazo[4,5-c]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 28.6 g / H₂; Raney Ni / methanol / 3.5 h / 20 °C

2: 20.1 g / acetic anhydride / 1.5 h / Heating

With hydrogen; acetic anhydride; nickel; In methanol;
DOI:10.1016/j.bmc.2005.10.040