1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-3-iodo-, ethyl ester

Base Information

• Chemical Name: 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-3-iodo-, ethyl ester
• CAS No.: 1132610-98-0
• Molecular Formula: C10H8ClIN2O2
• Molecular Weight: 350.54
• Hs Code.: 2933990090
• Mol file: 1132610-98-0.mol

Synonyms:SC4397;5-CHLORO-3-IODO-1H-PYRROLO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER;1H-PYRROLO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID,5-CHLORO-3-IODO-,ETHYL ESTER;ETHYL 5-CHLORO-3-IODO-7-AZAINDOLE-2-CARBOXYLATE;

Chemical Property of 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-3-iodo-, ethyl ester

Chemical Property:

• PKA: 9.48±0.40(Predicted)
• PSA: 54.98000
• Density: 1.910
• LogP: 2.99760

Purity/Quality:

NLT 98% ^*data from raw suppliers

Ethyl5-chloro-3-iodo-7-azaindole-2-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-3-iodo-, ethyl ester

There total 1 articles about 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-chloro-3-iodo-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H9ClN2O2 (1083181-28-5) → C10H8ClIN2O2 (1132610-98-0)

Guidance literature:

With N-iodo-succinimide; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 12h;

Reference yield:

C10H8ClIN2O2 (1132610-98-0) + 2-(bromomethyl)-1,4-difluorobenzene (85117-99-3) → C17H12ClF2IN2O2 (1132610-99-1)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 5h;

upstream raw materials:

C₁₀H₉ClN₂O₂

Downstream raw materials:

C₁₇H₁₂ClF₂IN₂O₂

Refernces