trans-8-decenoic acid

Base Information

• Chemical Name: trans-8-decenoic acid
• CAS No.: 85484-88-4
• Molecular Formula: C₁₀H₁₈O₂
• Molecular Weight: 170.252
• Mol file: 85484-88-4.mol

Synonyms:

Chemical Property of trans-8-decenoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-8-decenoic acid

There total 3 articles about trans-8-decenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

dec-9-enoic acid (14436-32-9) → (E)-dec-7-enoic acid (53036-81-0,21968-07-0) + trans-8-decenoic acid (85484-88-4)

Guidance literature:

With acetonitrile(cyclopentadienyl)[2-(di-i-propylphosphino)-4-(t-butyl)-1-methyl-1H-imidazole]ruthenium(II) hexafluorophosphate; In [⁽²⁾H₆]acetone; at 20 ℃; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1002/chem.201800728

Reference yield:

(7-carboxyheptyl)triphenylphosphonium bromide (52956-93-1) + acetaldehyde (75-07-0,9002-91-9) → 8-decenoic acid (62656-88-6) + trans-8-decenoic acid (85484-88-4)

Guidance literature:

(7-carboxyheptyl)triphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; at -20 ℃; for 1h; Inert atmosphere; Schlenk technique;

acetaldehyde; In tetrahydrofuran; at 20 ℃; Overall yield = 610 mg; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.202000620

Reference yield:

8-bromooctanoic acid (17696-11-6) → 8-decenoic acid (62656-88-6) + trans-8-decenoic acid (85484-88-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: acetonitrile / 168 h / 90 °C / Inert atmosphere; Schlenk technique

2.1: potassium tert-butylate / tetrahydrofuran / 1 h / -20 °C / Inert atmosphere; Schlenk technique

2.2: 20 °C / Inert atmosphere; Schlenk technique

With potassium tert-butylate; In tetrahydrofuran; acetonitrile;

DOI:10.1002/chem.202000620

upstream raw materials:

dec-9-enoic acid

(7-carboxyheptyl)triphenylphosphonium bromide

acetaldehyde

8-bromooctanoic acid