α-truxillic acid dimethylester

Base Information

• Chemical Name: α-truxillic acid dimethylester
• CAS No.: 2904-91-8
• Molecular Formula: C₂₀H₂₀O₄
• Molecular Weight: 324.376
• Mol file: 2904-91-8.mol

Synonyms:

Chemical Property of α-truxillic acid dimethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-truxillic acid dimethylester

There total 15 articles about α-truxillic acid dimethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.1%

α-truxillic acid (4462-95-7) + diazomethyl-trimethyl-silane (18107-18-1) → α-truxillic acid dimethylester (2904-91-8,56614-51-8)

Guidance literature:

In diethyl ether; butanone; for 1h;

DOI:10.1248/bpb.29.580

Reference yield:

Methyl cinnamate (103-26-4,1754-62-7) → α-truxillic acid dimethylester (2904-91-8,56614-51-8) + 3,4-diphenyl-cyclobutane-1,2-dicarboxylic acid dimethyl ester (160226-15-3)

Guidance literature:

boron trifluoride diethyl etherate; In dichloromethane; Quantum yield; Irradiation; other catalyst, absence catalyst;

DOI:10.1021/ja00314a059

Reference yield:

truxillic acid (490-20-0) → epitruxillic acid dimethyl ester (2904-91-8,56586-34-6,56614-51-8,100100-59-2,112530-29-7,112530-30-0)

Guidance literature:

Multi-step reaction with 4 steps

1: bei der thermischen Zersetzung; infolge intermediaerer Bildung von γ-Truxillsaeure-anhydrid

2: alcoholic KOH-solution

3: NaOH-solution

4: hydrochloric acid

With hydrogenchloride; potassium hydroxide; sodium hydroxide;

upstream raw materials:

methanol

γ-truxillic acid

ε-truxillic acid

Methyl cinnamate

Downstream raw materials:

2,4-diphenyl-cyclobutane-1,3-dicarboxylic acid monomethyl ester

ε-truxillic acid