GNE-490

Base Information

• Chemical Name: GNE-490
• CAS No.: 1033739-92-2
• Molecular Formula: C18H22N6O2S
• Molecular Weight: 386.47
• Mol file: 1033739-92-2.mol

Synonyms:3,6,9,12,15,18-Hexaoxanonacosan-1-ol;alcohol ethoxylate;

Chemical Property of GNE-490

Chemical Property:

• PSA: 139.25000
• LogP: 2.09800

Purity/Quality:

99% ^*data from raw suppliers

GNE-490 >98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of GNE-490

There total 1 articles about GNE-490 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methyl-5-(4,4,5,5-tetramethyl (1,3,2-dioxaborolan-2-yl))pyrimidine-2-ylamine (944401-55-2) + 2-(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)propan-2-ol (1033743-25-7) → GNE-490 (1033739-92-2)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In water; acetonitrile; at 140 ℃; for 0.25h; Microwave irradiation;

DOI:10.1021/jm901284w

upstream raw materials:

4-methyl-5-(4,4,5,5-tetramethyl (1,3,2-dioxaborolan-2-yl))pyrimidine-2-ylamine

2-(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)propan-2-ol

Refernces