Benzamide, 2-[[4-(dimethylamino)benzoyl]amino]-N-(4-methoxyphenyl)-5-[(methylsulfonyl)amino]-

Base Information

Chemical Name:Benzamide, 2-[[4-(dimethylamino)benzoyl]amino]-N-(4-methoxyphenyl)-5-[(methylsulfonyl)amino]-
CAS No.:263558-95-8
Molecular Formula:C24H26N4O5S
Molecular Weight:482.55
Hs Code.:
Mol file:263558-95-8.mol

Synonyms:2-[[4-(dimethylamino)benzoyl]amino]-5-(methanesulfonamido)-N-(4-methoxyphenyl)benzamide;BenzaMide, 2-[[4-(diMethylaMino)benzoyl]aMino]-N-(4-Methoxyphenyl)-5-[(Methylsulfonyl)aMino]-

Suppliers and Price of Benzamide, 2-[[4-(dimethylamino)benzoyl]amino]-N-(4-methoxyphenyl)-5-[(methylsulfonyl)amino]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-[[4-(DIMETHYLAMINO)BENZOYL]AMINO]-N-(4-METHOXYPHENYL)-5-[(METHYLSULFONYL)AMINO]BENZAMIDE 95.00%
5MG
$ 500.30

Total 4 raw suppliers

Chemical Property of Benzamide, 2-[[4-(dimethylamino)benzoyl]amino]-N-(4-methoxyphenyl)-5-[(methylsulfonyl)amino]-

Chemical Property:

PSA：125.22000
LogP:4.93710

Purity/Quality:

99% ^*data from raw suppliers

2-[[4-(DIMETHYLAMINO)BENZOYL]AMINO]-N-(4-METHOXYPHENYL)-5-[(METHYLSULFONYL)AMINO]BENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzamide, 2-[[4-(dimethylamino)benzoyl]amino]-N-(4-methoxyphenyl)-5-[(methylsulfonyl)amino]-

There total 7 articles about Benzamide, 2-[[4-(dimethylamino)benzoyl]amino]-N-(4-methoxyphenyl)-5-[(methylsulfonyl)amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

: 124-63-0
methanesulfonyl chloride

: 263558-93-6
5-Amino-2-(4-dimethylamino-benzoylamino)-N-(4-methoxy-phenyl)-benzamide

: 263558-95-8
2-(4-Dimethylamino-benzoylamino)-5-methanesulfonylamino-N-(4-methoxy-phenyl)-benzamide

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃; for 0.583333h;
DOI:10.1021/jm990327e

Reference yield:

: 4755-50-4
4-(dimethylamino)benzoyl chloride

: 263558-95-8
2-(4-Dimethylamino-benzoylamino)-5-methanesulfonylamino-N-(4-methoxy-phenyl)-benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine; DMAP / CH₂Cl₂ / 14 h

2: 86 percent / H₂ / 10 percent Pd/C / ethanol; ethyl acetate

3: 18 percent / pyridine / CH₂Cl₂ / 0.58 h / 0 - 20 °C

With pyridine; dmap; hydrogen; 10 percent Pd/C; In ethanol; dichloromethane; ethyl acetate; 1: Acylation / 2: Reduction / 3: Mesylation;
DOI:10.1021/jm990327e

Reference yield:

: 4693-02-1
6-nitroisatoic anhydride

: 263558-95-8
2-(4-Dimethylamino-benzoylamino)-5-methanesulfonylamino-N-(4-methoxy-phenyl)-benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / toluene / 5 h / Heating

2: pyridine; DMAP / CH₂Cl₂ / 14 h

3: 86 percent / H₂ / 10 percent Pd/C / ethanol; ethyl acetate

4: 18 percent / pyridine / CH₂Cl₂ / 0.58 h / 0 - 20 °C

With pyridine; dmap; hydrogen; 10 percent Pd/C; In ethanol; dichloromethane; ethyl acetate; toluene; 1: Ring cleavage / 2: Acylation / 3: Reduction / 4: Mesylation;
DOI:10.1021/jm990327e