Dimethyl 3-methoxy-5-methylphthalate

Base Information

• Chemical Name: Dimethyl 3-methoxy-5-methylphthalate
• CAS No.: 17284-66-1
• Molecular Formula: C₁₂H₁₄O₅
• Molecular Weight: 238.24
• DSSTox Substance ID: DTXSID801334541
• Mol file: 17284-66-1.mol

Synonyms:Dimethyl 3-methoxy-5-methylphthalate;17284-66-1;SCHEMBL9595637;DTXSID801334541

Chemical Property of Dimethyl 3-methoxy-5-methylphthalate

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 238.08412354
• Heavy Atom Count: 17
• Complexity: 289

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=C(C(=C1)OC)C(=O)OC)C(=O)OC

Technology Process of Dimethyl 3-methoxy-5-methylphthalate

There total 8 articles about Dimethyl 3-methoxy-5-methylphthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-methoxy-5-methyl-cyclohexa-1,4-diene (13697-84-2) + dimethyl acetylenedicarboxylate (762-42-5) → Dimethyl 3-methoxy-5-methylphthalate (17284-66-1)

Guidance literature:

Wilkinson's catalyst; at 140 ℃; for 18h;

DOI:10.1055/s-1982-29756

Reference yield:

6-methoxy-4-methyl-2H-pyran-2-one (67116-21-6) + dimethyl acetylenedicarboxylate (762-42-5) → Dimethyl 3-methoxy-5-methylphthalate (17284-66-1)

Guidance literature:

In toluene; Yield given; Heating;

DOI:10.1016/S0040-4039(00)80362-7

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 3-methoxy-5-methyl-phthalic acid (81722-05-6) → Dimethyl 3-methoxy-5-methylphthalate (17284-66-1)

Guidance literature:

With diethyl ether;

upstream raw materials:

diazomethane

3-methoxy-5-methyl-phthalic acid

1-methoxy-3-methyl-1,3-cyclohexadiene

dimethyl acetylenedicarboxylate

Downstream raw materials:

3-methoxy-5-methyl-phthalic acid