1H-Imidazo[2,1-f]purine-2,4(3H,8H)-dione, 7-(5-hydroxy-2-methylphenyl)-8-(2-methoxyphenyl)-1-methyl-

Base Information

Chemical Name:1H-Imidazo[2,1-f]purine-2,4(3H,8H)-dione, 7-(5-hydroxy-2-methylphenyl)-8-(2-methoxyphenyl)-1-methyl-
CAS No.:1192216-03-7
Molecular Formula:C22H19N5O4
Molecular Weight:417.41736
Hs Code.:
Mol file:1192216-03-7.mol

Synonyms:7-(5-hydroxy-2-methylphenyl)-6-(2-methoxyphenyl)-4-methylpurino[7,8-a]imidazole-1,3-dione;8-(2-methoxyphenyl)-1-methyl-7-(2-methyl-5-hydroxyphenyl)-1H-imidazo[2,1-f]-purine-2,4(3H,8H)-dione;1H-IMidazo[2,1-f]purine-2,4(3H,8H)-dione, 7-(5-hydroxy-2-Methylphenyl)-8-(2-Methoxyphenyl)-1-Methyl-

Suppliers and Price of 1H-Imidazo[2,1-f]purine-2,4(3H,8H)-dione, 7-(5-hydroxy-2-methylphenyl)-8-(2-methoxyphenyl)-1-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
7-(5-HYDROXY-2-METHYLPHENYL)-8-(2-METHOXYPHENYL)-1-METHYL-1H-IMIDAZO-[2,1-F]PURINE-2,4-(3H,8H)-DIONE 95.00%
5MG
$ 498.10

Total 2 raw suppliers

Chemical Property of 1H-Imidazo[2,1-f]purine-2,4(3H,8H)-dione, 7-(5-hydroxy-2-methylphenyl)-8-(2-methoxyphenyl)-1-methyl-

Chemical Property:

PSA：106.81000
LogP:2.76710

Purity/Quality:

99% ^*data from raw suppliers

7-(5-HYDROXY-2-METHYLPHENYL)-8-(2-METHOXYPHENYL)-1-METHYL-1H-IMIDAZO-[2,1-F]PURINE-2,4-(3H,8H)-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Imidazo[2,1-f]purine-2,4(3H,8H)-dione, 7-(5-hydroxy-2-methylphenyl)-8-(2-methoxyphenyl)-1-methyl-

There total 7 articles about 1H-Imidazo[2,1-f]purine-2,4(3H,8H)-dione, 7-(5-hydroxy-2-methylphenyl)-8-(2-methoxyphenyl)-1-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1192215-84-1
8-bromo-3,7-dihydro-3-methyl-7-[2-(2-methyl-5-hydroxyphenyl)-2-oxoethyl]-1H-purine-2,6-dione

: 90-04-0
2-methoxy-phenylamine

: 1192216-03-7
8-(2-methoxyphenyl)-1-methyl-7-(2-methyl-5-hydroxyphenyl)-1H-imidazo[2,1-f]-purine-2,4(3H,8H)-dione

Guidance literature:: With aluminum (III) chloride; In ethanol; at 175 ℃; for 72h;
DOI:10.1039/d0ob00391c

Reference yield: 45.0%

: 1192216-03-7
8-(2-methoxyphenyl)-1-methyl-7-(2-methyl-5-hydroxyphenyl)-1H-imidazo[2,1-f]-purine-2,4(3H,8H)-dione

Guidance literature:

Reference yield:

: 2434-53-9
6-amino-1-methyluracil

: 1192216-03-7
8-(2-methoxyphenyl)-1-methyl-7-(2-methyl-5-hydroxyphenyl)-1H-imidazo[2,1-f]-purine-2,4(3H,8H)-dione

Guidance literature:: Multi-step reaction with 6 steps

1: acetic acid; sodium nitrite / water / 1 h / 50 °C

2: sodium dithionite / water / 1 h / 70 °C

3: toluene-4-sulfonic acid / N,N-dimethyl-formamide / 3.5 h / 70 °C / Inert atmosphere

4: acetic acid; bromine; sodium acetate / 3 h / 65 °C

5: alkylamine / N,N-dimethyl-formamide / 16 h / 50 °C

6: aluminum (III) chloride / ethanol / 72 h / 175 °C

With aluminum (III) chloride; sodium dithionite; bromine; sodium acetate; toluene-4-sulfonic acid; acetic acid; sodium nitrite; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1039/d0ob00391c