2-(2-Chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole

Base Information

Chemical Name:2-(2-Chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
CAS No.:875787-07-8
Molecular Formula:C21H12ClF5N2
Molecular Weight:422.785
Hs Code.:
European Community (EC) Number:809-610-9
UNII:4W82FEU838
ChEMBL ID:CHEMBL456237
DSSTox Substance ID:DTXSID901026016
Nikkaji Number:J2.787.721D
Pharos Ligand ID:Y4B2LK4S2XRP
Wikidata:Q27260593
Mol file:875787-07-8.mol

Synonyms:2-(2-chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole;LXR 623;LXR-623;LXR623;WAY 252623;WAY-252623;WAY252623

Suppliers and Price of 2-(2-Chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
WAY252623
10mg
$ 135.00

TRC
WAY252623
5mg
$ 70.00

Tocris
WAY252623 ≥98%(HPLC)
10
$ 171.00

Tocris
WAY252623 ≥98%(HPLC)
50
$ 717.00

DC Chemicals
LXR623 >98%
1 g
$ 2000.00

CSNpharm
LXR-623
250mg
$ 753.00

CSNpharm
LXR-623
5mg
$ 48.00

CSNpharm
LXR-623
100mg
$ 512.00

Crysdot
LXR-623 98+%
50mg
$ 285.00

Crysdot
LXR-623 98+%
100mg
$ 507.00

Total 22 raw suppliers

Chemical Property of 2-(2-Chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole

Chemical Property:

Melting Point:93℃
Boiling Point:528.4±50.0 °C(Predicted)
PKA:-1.87±0.30(Predicted)
PSA：17.82000
Density:1.40
LogP:6.70200
Storage Temp.:room temp
XLogP3:6.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:422.0609169
Heavy Atom Count:29
Complexity:554

Purity/Quality:

99%, ^*data from raw suppliers

WAY252623 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(N(N=C2C(=C1)C(F)(F)F)CC3=C(C=C(C=C3)F)Cl)C4=CC=C(C=C4)F
Recent ClinicalTrials:Study Evaluating LXR-623 in Healthy Subjects
Uses WAY 252623 is a novel and potent LXR (liverX receptor) β-agonist used as a potential candidate for the treatment of atopic dermatitis.

Technology Process of 2-(2-Chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole

There total 1 articles about 2-(2-Chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%