45767-66-6

Basic information

• Product Name: 2-Chloro-4-fluorobenzyl bromide
• Synonyms: à-bromo-2-chloro-4-fluorotoluene;2-Chloro-4-fluorobenzyl bromide,99%;2-choro-4-fluorobenzylbromide;2-Chloro-4-fluorobenzyl broMide, 99% 2.5GR;2-Chloro-4-fluorobenzyl broMide, 99% 25GR;1-(Bromomethyl)-2-chloro-4-fluorobenzene, alpha-Bromo-2-chloro-4-fluorotoluene;(2-chloro-4-fluorophenyl)methyl bromide;TIMTEC-BB SBB005762
• CAS NO: 45767-66-6
• Molecular Formula: C₇H₅BrClF
• Molecular Weight: 223.47
• EINECS: 207-274-2
• Product Categories: Fluorine series
• Mol File: 45767-66-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 33-35°C
• Boiling Point: 226.8 °C at 760 mmHg
• Flash Point: 91 °C
• Appearance: White to yellow/Crystalline Low Melting Mass
• Density: 1.3879 (rough estimate)
• Vapor Pressure: 0.12mmHg at 25°C
• Refractive Index: 1.5550 (estimate)
• Storage Temp.: 0-10°C
• Solubility: soluble in Methanol
• Sensitive: Lachrymatory
• BRN: 3539265
• CAS DataBase Reference: 2-Chloro-4-fluorobenzyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4-fluorobenzyl bromide(45767-66-6)
• EPA Substance Registry System: 2-Chloro-4-fluorobenzyl bromide(45767-66-6)

Safety Data

• Hazard Codes: C,Xn
• Statements: 34-22
• Safety Statements: 45-36/37/39-26
• RIDADR: 3265
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 45767-66-6(Hazardous Substances Data)

Usage

Chemical Properties

white to light yellow crystal powder

InChI:InChI=1/C7H5BrClF/c8-4-5-1-2-6(10)3-7(5)9/h1-3H,4H2

Upstream product

• 452-73-3 2-chloro-4-fluorotoluene 
• 7440-33-7 tungsten 
• 112108-75-5 2-chloro-4-fluoro-5-diacetylaminobenzyl bromide 

Downstream Products

• 128833-98-7 2-chloro-4-fluorophenylalanine-hydrochloride 
• 300659-18-1 1-(2-chloro-4-fluorobenzyl)-2-(dimethylaminophenylmethyl)cyclohexanol, hydrochloride 
• 1146411-59-7 1-[(2-chloro-4-fluorophenyl)methyl]-4-[(2,3-dichlorophenyl)carbonyl]-2-piperazinone 
• 875787-07-8 WAY-252623 
• 919112-63-3 C₂₁H₃₂ClFN₂O₃S 
• 1221277-81-1 C₂₆H₂₁ClFNO₂S 
• 1221277-89-9 C₃₀H₂₉ClFNO₄S₂ 
• 1240660-12-1 3-acetyl-1-(2-chloro-4-fluorobenzyl)-4-methoxy-1H-indole 
• 868858-18-8 methyl (4S)-2-(2-chloro-4-fluorobenzyl)-5-[(2,6-dichlorophenyl)amino]-4-methyl-5-oxopentanoate 
• 887307-14-4 5-[(2-chloro-4-fluorophenyl)acetyl]-1-(2,6-dichlorophenyl)pyridin-2(1H)-one 
• 682759-19-9 C₁₂H₈ClFN₂O₃ 

Relevant articles and documents

HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION

A metallocene compound is represented by the formula (1): wherein: M is a Group 3, 4, 5 or 6 transition metal atom, or a lanthanide metal atom, or actinide metal atom, preferably a Group 4 transition metal atom selected from titanium, zirconium or hafnium; E is a substituted or unsubstituted monocyclic or polycyclic arenyl ligand pi-bonded to M; A is a substituted or unsubstituted polycyclic arenyl ligand that is pi-bonded to M and has a different ring structure than the E ligand; at least one of the A and E ligands includes at least one halogen substituent directly bonded to an sp2 carbon at a bondable ring position; Y is a bridging group containing at least one Group 13, 14, 15, or 16 element and any single position of the ring structure of A and to any single position of the ring structure of E; and y is zero or 1, indicating the absence (y = 0) or presence (y =1) of Y; and each X is a univalent anionic ligand, or two X are joined and bound to the metal atom to form a metallocycle ring, or two X are joined to form a chelating ligand, a diene ligand, or an alkylidene ligand; provided that when E is an unsubstituted cyclopentadienyl ligand, either y is one or A is not 2-bromofluorenyl or 2,7-dibromofluorenyl.

Herbicidal aryl tetrahydrophthalimides

A herbicidal compound of the formula STR1 where X is F, Cl or Br, Y is Cl, Br, CHF2 O or CF3, R is alkyl of 1 to 6 carbon atoms or lower halo alkyl and R' is H or lower alkyl. Related compounds, including those which have --SR or --NR2 R in place of --OR are also disclosed.

An Unusual Fluorine Atom Rearrangement in the Photocyclization of 1-Fluorohelicenes

Oxidative photocyclization of 1-fluorohelicene and two of its chlorine-substituted derivatives leads to the formation of 8-fluorobenzoperylenes through an unprecedented inter-ring fluorine atom migration; photoelimination of HF to give benzoperylenes also occurs as a competing process.The rearrangement pathway predominates when the irradiation is carried out at 0 deg C in air-saturated benzene solution containing 10 -3 M iodine; the elimination pathway predominates at higher temperatures or in the absence of either oxygen or iodine.The rearrangement isrationalized by postulating a triplet-state photocyclization to give a dihydrobenzoperylene intermediate, followed by abstraction of the tertiary hydrogen atom from that intermediate to give a radical that subsequently undergoes a fluorine atom shift by an SNi'mechanism.