2,3-Pyridinediamine, N3-[[5-(1H-indol-6-yl)-2-(phenylmethoxy)phenyl]methyl]-

Base Information

Chemical Name:2,3-Pyridinediamine, N3-[[5-(1H-indol-6-yl)-2-(phenylmethoxy)phenyl]methyl]-
CAS No.:892873-11-9
Molecular Formula:C₂₇H₂₄N₄O
Molecular Weight:420.514
Hs Code.:

Synonyms:3-N-[[5-(1H-indol-6-yl)-2-phenylmethoxyphenyl]methyl]pyridine-2,3-diamine;2,3-PyridinediaMine, N3-[[5-(1H-indol-6-yl)-2-(phenylMethoxy)phenyl]Methyl]-

Suppliers and Price of 2,3-Pyridinediamine, N3-[[5-(1H-indol-6-yl)-2-(phenylmethoxy)phenyl]methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N3-[[5-(1H-INDOL-6-YL)-2-(PHENYLMETHOXY)PHENYL]METHYL]-2,3-PYRIDINEDIAMINE 95.00%
5MG
$ 500.35

Total 1 raw suppliers

Chemical Property of 2,3-Pyridinediamine, N3-[[5-(1H-indol-6-yl)-2-(phenylmethoxy)phenyl]methyl]-

Chemical Property:

PSA：75.96000
LogP:6.65740

Purity/Quality:: N3-[[5-(1H-INDOL-6-YL)-2-(PHENYLMETHOXY)PHENYL]METHYL]-2,3-PYRIDINEDIAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,3-Pyridinediamine, N3-[[5-(1H-indol-6-yl)-2-(phenylmethoxy)phenyl]methyl]-

There total 5 articles about 2,3-Pyridinediamine, N3-[[5-(1H-indol-6-yl)-2-(phenylmethoxy)phenyl]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 892872-44-5
N³-(2-benzyloxy-5-bromobenzyl)pyridine-2,3-diamine

: 147621-18-9
6-indolylboronic acid

: 892873-11-9
N~3~-[2-(benzyloxy)-5-(1H-indol-6-yl)-benzyl]pyridine-2,3-diamine

Guidance literature:: With potassium carbonate; bis(tri-tert-butylphosphine)palladium⁽⁰⁾; In methanol; ethanol; at 135 ℃; for 0.25h; microwave irradiation;
DOI:10.1021/jm061197u

Reference yield:

: 121124-94-5
2-benzyloxy-5-bromobenzaldehyde

: 892873-11-9
N~3~-[2-(benzyloxy)-5-(1H-indol-6-yl)-benzyl]pyridine-2,3-diamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / CH₂Cl₂ / 0.17 h / 20 °C

1.2: 43 percent / NaBH(OAc)3 / CH₂Cl₂ / 20 °C

2.1: 48 percent / potassium carbonate / bis(tri-tert-butylphosphine)palladium⁽⁰⁾ / methanol; ethanol; various solvent(s) / 0.25 h / 135 °C / microwave irradiation

With potassium carbonate; acetic acid; bis(tri-tert-butylphosphine)palladium⁽⁰⁾; In methanol; ethanol; dichloromethane;
DOI:10.1021/jm061197u

Reference yield:

: 100-39-0
benzyl bromide

: 892873-11-9
N~3~-[2-(benzyloxy)-5-(1H-indol-6-yl)-benzyl]pyridine-2,3-diamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: 88 percent / potassium carbonate / tetrahydrofuran / 16 h / Heating

2.1: acetic acid / CH₂Cl₂ / 0.17 h / 20 °C

2.2: 43 percent / NaBH(OAc)3 / CH₂Cl₂ / 20 °C

3.1: 48 percent / potassium carbonate / bis(tri-tert-butylphosphine)palladium⁽⁰⁾ / methanol; ethanol; various solvent(s) / 0.25 h / 135 °C / microwave irradiation

With potassium carbonate; acetic acid; bis(tri-tert-butylphosphine)palladium⁽⁰⁾; In tetrahydrofuran; methanol; ethanol; dichloromethane;
DOI:10.1021/jm061197u