Technology Process of cis-3,3-dicyano-7,7-diphenyl-5-isopropyl-2-methyl-4,6-heptadiene
There total 5 articles about cis-3,3-dicyano-7,7-diphenyl-5-isopropyl-2-methyl-4,6-heptadiene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydride;
Yield given. Multistep reaction;
1.) 1,2-dimethoxyethane, 10 min, 2.) 32 h;
DOI:10.1021/jo00277a013
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) LDA / 1.) THF, -78 deg C, 10 min, 2a.) -78 deg C, 2b.) room temp., 18 h
2: 92 percent / 1.0 M diisobutylaluminum hydride / hexane / 2.5 h / Ambient temperature
3: 90 percent / CrO3, pyridine / CH2Cl2 / 1.5 h
4: 98 percent / β-alanine / acetic acid; benzene / 0.75 h / Heating
5: 1.) NaH / 1.) 1,2-dimethoxyethane, 10 min, 2.) 32 h
With
pyridine; chromium(VI) oxide; sodium hydride; diisobutylaluminium hydride; lithium diisopropyl amide; 3-amino propanoic acid;
In
hexane; dichloromethane; acetic acid; benzene;
DOI:10.1021/jo00277a013
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 90 percent / CrO3, pyridine / CH2Cl2 / 1.5 h
2: 98 percent / β-alanine / acetic acid; benzene / 0.75 h / Heating
3: 1.) NaH / 1.) 1,2-dimethoxyethane, 10 min, 2.) 32 h
With
pyridine; chromium(VI) oxide; sodium hydride; 3-amino propanoic acid;
In
dichloromethane; acetic acid; benzene;
DOI:10.1021/jo00277a013
