2-Methyl-4-(4-nitro-phenyl)-6-{2-[4-(2,3,4-trimethoxy-benzyl)-piperazin-1-yl]-ethyl}-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester; hydrochloride

Base Information

Chemical Name:2-Methyl-4-(4-nitro-phenyl)-6-{2-[4-(2,3,4-trimethoxy-benzyl)-piperazin-1-yl]-ethyl}-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester; hydrochloride
CAS No.:75994-10-4
Molecular Formula:C₃₂H₄₀N₄O₉*2ClH
Molecular Weight:697.613
Hs Code.:

2-Methyl-4-(4-nitro-phenyl)-6-{2-[4-(2,3,4-trimethoxy-benzyl)-piperazin-1-yl]-ethyl}-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester; hydrochloride

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Chemical Property of 2-Methyl-4-(4-nitro-phenyl)-6-{2-[4-(2,3,4-trimethoxy-benzyl)-piperazin-1-yl]-ethyl}-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester; hydrochloride

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Technology Process of 2-Methyl-4-(4-nitro-phenyl)-6-{2-[4-(2,3,4-trimethoxy-benzyl)-piperazin-1-yl]-ethyl}-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester; hydrochloride

There total 1 articles about 2-Methyl-4-(4-nitro-phenyl)-6-{2-[4-(2,3,4-trimethoxy-benzyl)-piperazin-1-yl]-ethyl}-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 127881-54-3
1-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride

: 21829-09-4,161838-99-9
4-(4-nitrophenyl)-2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydropyridine

: 75994-10-4
2-Methyl-4-(4-nitro-phenyl)-6-{2-[4-(2,3,4-trimethoxy-benzyl)-piperazin-1-yl]-ethyl}-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester; hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; for 16h; Heating; 2- to 3-fold molar excess of paraformaldehyde and secondary amine hydrochloride;
DOI:10.1248/cpb.28.3163