3-(4-Fluorophenyl)-3-pyrrolidinol

Base Information

Chemical Name:3-(4-Fluorophenyl)-3-pyrrolidinol
CAS No.:577986-35-7
Molecular Formula:C10H12FNO
Molecular Weight:181.21
Hs Code.:
Mol file:577986-35-7.mol

Synonyms:3-Hydroxy-3-(4-fluor-phenyl)-pyrrolidin;3-(4-Fluoro-phenyl)-pyrrolidin-3-ol;3-(4-FLUOROPHENYL)PYRROLIDIN-3-OL;3-(4-Fluorophenyl)-3-pyrrolidinol HCl;3-Hydroxy-3-<4-fluor-phenyl>-pyrrolidin;

Suppliers and Price of 3-(4-Fluorophenyl)-3-pyrrolidinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(4-Fluorophenyl)-3-pyrrolidinolHydrochloride
100mg
$ 330.00

Acrotein
3-(4-Fluorophenyl)-3-pyrrolidinolHCl 97%
0.25g
$ 146.67

Total 7 raw suppliers

Chemical Property of 3-(4-Fluorophenyl)-3-pyrrolidinol

Chemical Property:

PSA：32.26000
LogP:1.33540

Purity/Quality:

99% ^*data from raw suppliers

3-(4-Fluorophenyl)-3-pyrrolidinolHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(4-Fluorophenyl)-3-pyrrolidinol

There total 3 articles about 3-(4-Fluorophenyl)-3-pyrrolidinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 425663-33-8
1-benzyl-3-(4-fluoro-phenyl)-pyrrolidin-3-ol

: 577986-35-7
3-(4-fluoro-phenyl)-pyrrolidin-3-ol

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 16h; under 2585.74 Torr;
DOI:10.1021/jm990316l

Reference yield:

: 352-13-6
4-flourophenylmagnesium bromide

: 577986-35-7
3-(4-fluoro-phenyl)-pyrrolidin-3-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 600 mg / tetrahydrofuran; diethyl ether / 18 h / 20 °C

2: 100 percent / H₂ / 10 percent Pd/C / methanol / 16 h / 20 °C / 2585.74 Torr

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; 1: Addition / 2: Hydrogenolysis;
DOI:10.1021/jm990316l

Reference yield:

: 577986-35-7
3-(4-fluoro-phenyl)-pyrrolidin-3-ol

Guidance literature:: 3-Hydroxy-3-<4-fluor-phenyl>-pyrrolidin-1-carbonsaeureaethylester 1. Propanol-(2), konz. wss. KOH, Sdet., 20h 2. aethanol. HCl;
DOI:10.1021/jm00331a014