Bis(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfide

Base Information

• Chemical Name: Bis(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfide
• CAS No.: 4073-59-0
• Molecular Formula: C10H20O4P2S4
• Molecular Weight: 394.478
• Mol file: 4073-59-0.mol

Synonyms:Bis(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfide

Chemical Property of Bis(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfide

Chemical Property:

• PSA: 171.32000
• LogP: 6.26400

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Bis(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfide

There total 10 articles about Bis(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfanyl]dodecane (934499-56-6) → didodecyl disulfide (2757-37-1) + bis-(5,5-dimethyl-2-thiono-1,3,2-dioxaphosphorinan-2-yl)disulfide (4073-59-0)

Guidance literature:

With sodium hydride; Acetanilid; In tetrahydrofuran; mineral oil; at 20 ℃; for 16h; Reagent/catalyst; Inert atmosphere;

DOI:10.1080/10426507.2015.1065258

Reference yield: 85.0%

5,5-dimethyl-2-sulfanyl-2-thioxo-1,3,2-dioxaphosphorinane ammonium salt (74862-75-2) → bis-(5,5-dimethyl-2-thiono-1,3,2-dioxaphosphorinan-2-yl)disulfide (4073-59-0)

Guidance literature:

With iodine; potassium iodide; In water; at 20 ℃;

DOI:10.1055/s-0033-1338966

Reference yield: 65.0%

3,4,6-tri-O-acetyl-1,5-anhydro-2-bromo-2-deoxy-D-arabino-hex-1-enitol (65784-92-1) + 5,5-dimethyl-2-thiolo-2-thiono-1,3,2-dioxaphosphorinane (697-45-0) → bis-(5,5-dimethyl-2-thiono-1,3,2-dioxaphosphorinan-2-yl)disulfide (4073-59-0) + 2-(3,4,6-tri-O-acetyl-2-bromo-2-deoxy-α-D-gluco-pyranosyl)-thio-2-thiono-5,5-dimethyl-1,3,2-dioxaphosphorinane + 2-(3,4,6-tri-O-acetyl-2-bromo-2-deoxy-β-D-gluco-pyranosyl)-thio-2-thiono-5,5-dimethyl-1,3,2-dioxaphosphorinane (224184-72-9)

Guidance literature:

In benzene; at 80 ℃; Heating;

upstream raw materials:

5,5-dimethyl-2-sulfanyl-2-thioxo-1,3,2-dioxaphosphorinane ammonium salt

3,4,6-tri-O-acetyl-1,5-anhydro-2-bromo-2-deoxy-D-arabino-hex-1-enitol

5,5-dimethyl-2-thiolo-2-thiono-1,3,2-dioxaphosphorinane

3,4,6-tri-O-acetyl-2-bromo-2-deoxy-α-D-mannopyramnosyl bromide

Downstream raw materials:

trimethylsilyl isothiocyanate

bis-(5,5-dimethyl-2-thiono-1,3,2-dioxaphosphorinan-2-yl)sulfide

5,5-Dimethyl-2-trimethylsilanylsulfanyl-[1,3,2]dioxaphosphinane 2-sulfide

4-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfanyl]anisole