glycolithocholic acid

Base Information

• Chemical Name: glycolithocholic acid
• CAS No.: 13164-19-7
• Molecular Formula: C₂₆H₄₃NO₄
• Molecular Weight: 433.632
• Mol file: 13164-19-7.mol

Synonyms:

Chemical Property of glycolithocholic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of glycolithocholic acid

There total 5 articles about glycolithocholic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl N-(3α-hydroxy-5β-cholan-24-oyl)glycinate (69320-20-3) → glycolithocholic acid (13164-19-7,69351-31-1,78479-09-1,139894-84-1,474-74-8)

Guidance literature:

methyl N-(3α-hydroxy-5β-cholan-24-oyl)glycinate; With sodium hydroxide; In ethanol; at 20 ℃; for 1h;

With hydrogenchloride; In water;

DOI:10.1021/jm301890k

Reference yield: 69.0%

C30H51NO4 (881179-18-6) → glycolithocholic acid (13164-19-7,69351-31-1,78479-09-1,139894-84-1,474-74-8)

Guidance literature:

With water; trifluoroacetic acid; at 20 ℃; for 1h;

DOI:10.1039/b514915k

Reference yield:

Lithocholic acid (434-13-9) → glycolithocholic acid (13164-19-7,69351-31-1,78479-09-1,139894-84-1,474-74-8)

Guidance literature:

With 1,4-dioxane; tributyl-amine; chloroformic acid ethyl ester; anschliessend Behandeln mit Natriumglycinat in H₂O;

upstream raw materials:

Lithocholic acid

C₃₀H₅₁NO₄

methyl N-(3α-hydroxy-5β-cholan-24-oyl)glycinate