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Product FOB Price Min.Order Supply Ability Supplier
Lithocholic Acid
Cas No: 434-13-9
No Data 1 Kilogram 100 Kilogram/Month Jiangsu Ruda Bioengineering Co. Ltd Contact Supplier
Lithocholic Acid
Cas No: 434-13-9
USD $ 3.6-3.6 / Metric Ton 1 Metric Ton 1000 Metric Ton/Year Antimex Chemical Limied Contact Supplier
Cholan-24-oic acid,3-hydroxy-, (3a,5b)-
Cas No: 434-13-9
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
CAS 434-13-9 Lithocholic Acid high purity
Cas No: 434-13-9
USD $ 10.0-10.0 / Gram 1 Gram 10000 Kilogram/Month Hubei Vanz Pharm Co.,Ltd Contact Supplier
High quality Lithocholic Acid Cas 434-13-9 with fast delivery
Cas No: 434-13-9
USD $ 890.0-896.0 / Kilogram 1 Kilogram 3 Metric Ton/Year Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
High Quality 99% Lithocholic Acid 434-13-9 GMP Manufacturer
Cas No: 434-13-9
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
Lithocholic acid
Cas No: 434-13-9
No Data 10 Milligram 1 Kilogram/Day shanghai Tauto Biotech Co., Ltd Contact Supplier
Pharmaceutical grade Lithocholic acid CAS 434-13-9
Cas No: 434-13-9
USD $ 1.0-2.0 / Kilogram 1 Kilogram 10 Metric Ton/Quarter Shaanxi Greenyo Biotech Co., Ltd. Contact Supplier
LITHOCHOLIC ACID
Cas No: 434-13-9
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
Lithocholic acid
Cas No: 434-13-9
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier

434-13-9 Usage

Chemical Properties

white to off-white powder

Purification Methods

Lithocholic acid can be purified by conversion to the rather insoluble Na or K salt by addition of the equivalent amount of aqueous NaOH or KOH, filtering off the alkali salt, washing it with ice cold H2O, dissolving it in the least volume of boiling H2O, acidifying with the dilute HCl (slight excess), filtering off the acid, washing with cold H2O and drying it thoroughly in a vacuum. Recrystallise it from Me2CO, EtOH or acetic acid. The methyl ester crystallises from MeOH, with 0.5 mol of MeOH, and has m 92-93o, [] D 25 +34o (MeOH). It has also been purified by recrystallisation from pet ether (b 40-60o) and, after chromatography on Al2O3 in pet ether, gave a labile form m 92-93o which is transformed to the stable form m 125-126o after standing for 2days in a vacuum desiccator. [Hoelm & Mason J Am Chem Soc 62 569 1940, Sarel & Yanuka J Org Chem 24 2018 1959, Beilstein 10 IV 785.]

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition LITHOCHOLIC ACID emits acrid smoke and fumes.

Fire Hazard

Flash point data for LITHOCHOLIC ACID are not available. LITHOCHOLIC ACID is probably combustible.

Definition

ChEBI: A monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action.

General Description

Hexagonal leaflets (from alcohols) or prisms (from acetic acid) or white powder.

Uses

LD50(mouse) 3900 mg/kg po

Uses

A cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones.

Air & Water Reactions

Insoluble in water.

Uses

Cholagogue;Anticholelithogenic
InChI:InChI=1/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/p-1/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1

434-13-9 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
TCI America (L0089)  Lithocholic Acid  >98.0%(T) 434-13-9 5g 490.00CNY Detail
TCI America (L0089)  Lithocholic Acid  >98.0%(T) 434-13-9 25g 1,390.00CNY Detail
Sigma-Aldrich (L0720800)  Lithocholicacid  European Pharmacopoeia (EP) Reference Standard 434-13-9 L0720800 1,880.19CNY Detail
Sigma (L6250)  Lithocholicacid  ≥95% 434-13-9 L6250-10G 548.73CNY Detail
Sigma (L6250)  Lithocholicacid  ≥95% 434-13-9 L6250-25G 1,187.55CNY Detail

434-13-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name lithocholic acid

1.2 Other means of identification

Product number -
Other names 3α-Hydroxy-5β-cholanic Acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:434-13-9 SDS

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